Deleting fis downregulates virulence and effectively protects Pasteurella multocida infection in mice

Deleting fis downregulates virulence and effectively protects Pasteurella multocida infection in mice

Abstract Pasteurella multocida (P. multocida) is an important pathogen causing various diseases in both domestic and wild animals. The factor for inversion stimulation (Fis) is a nucleoid-associated protein with diverse functions in various bacteria, which positively regulate the transcription of ca...

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Bibliographic Details
Main Authors:	Zhijie Wang, Siyu Liu, Muhan Xie, Zhengchun Lang, Xuan Zhang, Liang Luo, Guangfu Zhao, Nengzhang Li, Yuanyi Peng
Format:	Article
Language:	English
Published:	BMC 2025-05-01
Series:	BMC Veterinary Research
Subjects:	Pasteurella multocida Fis gene Capsule Iron utilization Virulence Vaccine
Online Access:	https://doi.org/10.1186/s12917-025-04769-x
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