A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity.

A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity.

Asthma is a chronic inflammatory disease of the airways with contributions from genes, environmental exposures, and their interactions. While genome-wide association studies (GWAS) in humans have identified ~200 susceptibility loci, the genetic factors that modulate risk of asthma through gene-envir...

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Main Authors: Hadi Maazi, Jaana A Hartiala, Yuzo Suzuki, Amanda L Crow, Pedram Shafiei Jahani, Jonathan Lam, Nisheel Patel, Diamanda Rigas, Yi Han, Pin Huang, Eleazar Eskin, Aldons J Lusis, Frank D Gilliland, Omid Akbari, Hooman Allayee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1008528&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1008528&type=printable

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