Development of a compact cavity BPM for real-time monitoring of clinical proton beams at HUST-PTF

IntroductionTo ensure the safety and efficacy of precise proton therapy, real-time and non-intrusive monitoring of the clinical beam position is essential. However, in cyclotron-based proton therapy facilities, clinical proton beams with low repetition frequency and exceptionally low intensity due t...

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Main Authors: Jiqing Li, Yuexin Lu, Jiapeng Li, Jian Wang, Zhengzheng Liu, Oleg Meshkov, Jinfeng Yang, Kuanjun Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1508361/full
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author Jiqing Li
Yuexin Lu
Jiapeng Li
Jian Wang
Zhengzheng Liu
Oleg Meshkov
Jinfeng Yang
Kuanjun Fan
author_facet Jiqing Li
Yuexin Lu
Jiapeng Li
Jian Wang
Zhengzheng Liu
Oleg Meshkov
Jinfeng Yang
Kuanjun Fan
author_sort Jiqing Li
collection DOAJ
description IntroductionTo ensure the safety and efficacy of precise proton therapy, real-time and non-intrusive monitoring of the clinical beam position is essential. However, in cyclotron-based proton therapy facilities, clinical proton beams with low repetition frequency and exceptionally low intensity due to the Energy Selection Systems (ESS), pose considerable challenges for accurate online beam diagnostics. Conventional non-interceptive beam diagnostic devices lack the sensitivity required to detect such weak beams with sufficient precision.MethodsThis paper presents an innovative solution to this challenge: an off-centerrectangular cavity Beam Position Monitor (BPM) with dielectric loading. This novel design achieves remarkable position sensitivity while maintaining compact transverse dimensions of 500×250×100 mm.ResultsA prototype of this cavity has been fabricated and tested offline. Experimental results demonstrate that, within the clinical treatment energy range, the BPM achieves minimum beam position measurement sensitivities of 0.49 nV/mm at 70 MeV and 17.12 nV/mm at 230 MeV. In addition to enabling online beam position monitoring without disturbing the beam path, which ensures real-time beam orbit feedback correction with submillimeter stability (± 0.5 mm).DiscussionIn addition to monitoring beam positions for precise control of the beam orbit, the BPMs could serve additional functions to enhance proton therapy—such as enabling beam energy verification through the phase of the BPM signal.
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publishDate 2025-06-01
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spelling doaj-art-4a71b1550e4a4e5491cc6ffda66351c32025-08-20T03:32:15ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-06-011510.3389/fonc.2025.15083611508361Development of a compact cavity BPM for real-time monitoring of clinical proton beams at HUST-PTFJiqing Li0Yuexin Lu1Jiapeng Li2Jian Wang3Zhengzheng Liu4Oleg Meshkov5Jinfeng Yang6Kuanjun Fan7State Key Laboratory of Advanced Electromagnetic Technology, Huazhong University of Science and Technology, Wuhan, ChinaState Key Laboratory of Advanced Electromagnetic Technology, Huazhong University of Science and Technology, Wuhan, ChinaState Key Laboratory of Advanced Electromagnetic Technology, Huazhong University of Science and Technology, Wuhan, ChinaState Key Laboratory of Advanced Electromagnetic Technology, Huazhong University of Science and Technology, Wuhan, ChinaState Key Laboratory of Advanced Electromagnetic Technology, Huazhong University of Science and Technology, Wuhan, ChinaBudker Institute of Nuclear Physics SB RAS, Novosibirsk, RussiaInstitute of Scientific and Industrial Research, Osaka University, Osaka, JapanState Key Laboratory of Advanced Electromagnetic Technology, Huazhong University of Science and Technology, Wuhan, ChinaIntroductionTo ensure the safety and efficacy of precise proton therapy, real-time and non-intrusive monitoring of the clinical beam position is essential. However, in cyclotron-based proton therapy facilities, clinical proton beams with low repetition frequency and exceptionally low intensity due to the Energy Selection Systems (ESS), pose considerable challenges for accurate online beam diagnostics. Conventional non-interceptive beam diagnostic devices lack the sensitivity required to detect such weak beams with sufficient precision.MethodsThis paper presents an innovative solution to this challenge: an off-centerrectangular cavity Beam Position Monitor (BPM) with dielectric loading. This novel design achieves remarkable position sensitivity while maintaining compact transverse dimensions of 500×250×100 mm.ResultsA prototype of this cavity has been fabricated and tested offline. Experimental results demonstrate that, within the clinical treatment energy range, the BPM achieves minimum beam position measurement sensitivities of 0.49 nV/mm at 70 MeV and 17.12 nV/mm at 230 MeV. In addition to enabling online beam position monitoring without disturbing the beam path, which ensures real-time beam orbit feedback correction with submillimeter stability (± 0.5 mm).DiscussionIn addition to monitoring beam positions for precise control of the beam orbit, the BPMs could serve additional functions to enhance proton therapy—such as enabling beam energy verification through the phase of the BPM signal.https://www.frontiersin.org/articles/10.3389/fonc.2025.1508361/fullproton therapybeam position monitorcavityshunt impedanceoff-centerdielectric loading
spellingShingle Jiqing Li
Yuexin Lu
Jiapeng Li
Jian Wang
Zhengzheng Liu
Oleg Meshkov
Jinfeng Yang
Kuanjun Fan
Development of a compact cavity BPM for real-time monitoring of clinical proton beams at HUST-PTF
Frontiers in Oncology
proton therapy
beam position monitor
cavity
shunt impedance
off-center
dielectric loading
title Development of a compact cavity BPM for real-time monitoring of clinical proton beams at HUST-PTF
title_full Development of a compact cavity BPM for real-time monitoring of clinical proton beams at HUST-PTF
title_fullStr Development of a compact cavity BPM for real-time monitoring of clinical proton beams at HUST-PTF
title_full_unstemmed Development of a compact cavity BPM for real-time monitoring of clinical proton beams at HUST-PTF
title_short Development of a compact cavity BPM for real-time monitoring of clinical proton beams at HUST-PTF
title_sort development of a compact cavity bpm for real time monitoring of clinical proton beams at hust ptf
topic proton therapy
beam position monitor
cavity
shunt impedance
off-center
dielectric loading
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1508361/full
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