Eradication Therapy for Pediatric Helicobacter pylori Infection
In children, Helicobacter pylori infection causes gastritis, peptic ulcer, and extraintestinal manifestations such as refractory iron deficiency anemia, failure to thrive, and chronic idiopathic thrombocytopenia. The outcomes of recommendations for H. pylori eradication therapy in children are not c...
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| Format: | Article |
| Language: | English |
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Korean College of Helicobacter and Upper Gastrointestinal Research
2017-03-01
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| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
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| Online Access: | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.1.16 |
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| _version_ | 1849710966692904960 |
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| author | Ji-Hyun Seo Hee-Shang Youn |
| author_facet | Ji-Hyun Seo Hee-Shang Youn |
| author_sort | Ji-Hyun Seo |
| collection | DOAJ |
| description | In children, Helicobacter pylori infection causes gastritis, peptic ulcer, and extraintestinal manifestations such as refractory iron deficiency anemia, failure to thrive, and chronic idiopathic thrombocytopenia. The outcomes of recommendations for H. pylori eradication therapy in children are not comparable with the eradication rates of those in adults because of the low level of evidence, including randomized placebo-controlled treatment trials. In South Korea, no standard guideline for the management of children with H. pylori infection has been established yet. Herein, we reviewed the indications for and various modalities of eradication therapy in children with H. pylori infection in accordance with a review of published articles. H. pylori-associated peptic ulcer is the only one indication for eradication therapy. A proton pump inhibitor based on a combination of two antibiotics has been considered as the standard eradication therapy in children, but no consensus has been reached regarding the modality of eradication therapy in children. |
| format | Article |
| id | doaj-art-4a6a86369f4e433b8ebbe76ce6f8aa78 |
| institution | DOAJ |
| issn | 1738-3331 |
| language | English |
| publishDate | 2017-03-01 |
| publisher | Korean College of Helicobacter and Upper Gastrointestinal Research |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj-art-4a6a86369f4e433b8ebbe76ce6f8aa782025-08-20T03:14:45ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312017-03-01171161910.7704/kjhugr.2017.17.1.16kjhugr.2017.17.1.16Eradication Therapy for Pediatric Helicobacter pylori InfectionJi-Hyun Seo0Hee-Shang Youn1Department of Pediatrics, Gyeongsang National University School of Medicine, Jinju, KoreaDepartment of Pediatrics, Gyeongsang National University School of Medicine, Jinju, KoreaIn children, Helicobacter pylori infection causes gastritis, peptic ulcer, and extraintestinal manifestations such as refractory iron deficiency anemia, failure to thrive, and chronic idiopathic thrombocytopenia. The outcomes of recommendations for H. pylori eradication therapy in children are not comparable with the eradication rates of those in adults because of the low level of evidence, including randomized placebo-controlled treatment trials. In South Korea, no standard guideline for the management of children with H. pylori infection has been established yet. Herein, we reviewed the indications for and various modalities of eradication therapy in children with H. pylori infection in accordance with a review of published articles. H. pylori-associated peptic ulcer is the only one indication for eradication therapy. A proton pump inhibitor based on a combination of two antibiotics has been considered as the standard eradication therapy in children, but no consensus has been reached regarding the modality of eradication therapy in children.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.1.16Helicobacter pyloriChildTherapeutics |
| spellingShingle | Ji-Hyun Seo Hee-Shang Youn Eradication Therapy for Pediatric Helicobacter pylori Infection The Korean Journal of Helicobacter and Upper Gastrointestinal Research Helicobacter pylori Child Therapeutics |
| title | Eradication Therapy for Pediatric Helicobacter pylori Infection |
| title_full | Eradication Therapy for Pediatric Helicobacter pylori Infection |
| title_fullStr | Eradication Therapy for Pediatric Helicobacter pylori Infection |
| title_full_unstemmed | Eradication Therapy for Pediatric Helicobacter pylori Infection |
| title_short | Eradication Therapy for Pediatric Helicobacter pylori Infection |
| title_sort | eradication therapy for pediatric helicobacter pylori infection |
| topic | Helicobacter pylori Child Therapeutics |
| url | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.1.16 |
| work_keys_str_mv | AT jihyunseo eradicationtherapyforpediatrichelicobacterpyloriinfection AT heeshangyoun eradicationtherapyforpediatrichelicobacterpyloriinfection |