The Emergence of <i>Bacteroides pyogenes</i> as a Human Pathogen of Animal Origin: A Narrative Review
<i>Bacteroides pyogenes</i> is a Gram-negative obligate anaerobe rod. It is naturally found in the oral microbiome of cats and dogs, which represents a primary source of disease for humans. The present review provides an update on the role of <i>B. pyogenes</i> as a pathogen...
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MDPI AG
2025-05-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/13/6/1200 |
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| author | Carola Mauri Chiara Giubbi Alessandra Consonni Elena Briozzo Elisa Meroni Francesco Luzzaro Silvia Tonolo |
| author_facet | Carola Mauri Chiara Giubbi Alessandra Consonni Elena Briozzo Elisa Meroni Francesco Luzzaro Silvia Tonolo |
| author_sort | Carola Mauri |
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| description | <i>Bacteroides pyogenes</i> is a Gram-negative obligate anaerobe rod. It is naturally found in the oral microbiome of cats and dogs, which represents a primary source of disease for humans. The present review provides an update on the role of <i>B. pyogenes</i> as a pathogen responsible for infections in humans. Indeed, an increasing number of <i>B. pyogenes</i> infections have been reported in recent years, including skin and soft tissue infections as well as severe diseases like osteomyelitis, Lemierre’s syndrome, and bloodstream infection. Pre-analytical and analytical phases are crucial to guarantee the isolation of anaerobic bacteria, including <i>B. pyogenes</i>. Moreover, the introduction of MALDI-TOF mass spectrometry and 16S rRNA sequencing in clinical microbiology laboratories may be partially responsible for the increasing number of reports of <i>B. pyogenes</i> infections. However, the mechanisms underlying the pathogenicity of <i>B. pyogenes</i> remain poorly understood and require further investigations. Indeed, despite common antimicrobial susceptibilities, infections frequently persist and require multiple courses of antibiotics. In addition, based on literature data, this review indicates that treatment of skin and soft tissue infections often necessitates surgical procedures and hospitalization. |
| format | Article |
| id | doaj-art-4a69dbb847044c58adc1aee48cecdb28 |
| institution | Kabale University |
| issn | 2076-2607 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj-art-4a69dbb847044c58adc1aee48cecdb282025-08-20T03:27:32ZengMDPI AGMicroorganisms2076-26072025-05-01136120010.3390/microorganisms13061200The Emergence of <i>Bacteroides pyogenes</i> as a Human Pathogen of Animal Origin: A Narrative ReviewCarola Mauri0Chiara Giubbi1Alessandra Consonni2Elena Briozzo3Elisa Meroni4Francesco Luzzaro5Silvia Tonolo6Clinical Microbiology and Virology Unit, “A. Manzoni” Hospital, 23900 Lecco, ItalyClinical Microbiology and Virology Unit, “A. Manzoni” Hospital, 23900 Lecco, ItalyClinical Microbiology and Virology Unit, “A. Manzoni” Hospital, 23900 Lecco, ItalyClinical Microbiology and Virology Unit, “A. Manzoni” Hospital, 23900 Lecco, ItalyClinical Microbiology and Virology Unit, “A. Manzoni” Hospital, 23900 Lecco, ItalyClinical Microbiology and Virology Unit, “A. Manzoni” Hospital, 23900 Lecco, ItalyClinical Microbiology and Virology Unit, “A. Manzoni” Hospital, 23900 Lecco, Italy<i>Bacteroides pyogenes</i> is a Gram-negative obligate anaerobe rod. It is naturally found in the oral microbiome of cats and dogs, which represents a primary source of disease for humans. The present review provides an update on the role of <i>B. pyogenes</i> as a pathogen responsible for infections in humans. Indeed, an increasing number of <i>B. pyogenes</i> infections have been reported in recent years, including skin and soft tissue infections as well as severe diseases like osteomyelitis, Lemierre’s syndrome, and bloodstream infection. Pre-analytical and analytical phases are crucial to guarantee the isolation of anaerobic bacteria, including <i>B. pyogenes</i>. Moreover, the introduction of MALDI-TOF mass spectrometry and 16S rRNA sequencing in clinical microbiology laboratories may be partially responsible for the increasing number of reports of <i>B. pyogenes</i> infections. However, the mechanisms underlying the pathogenicity of <i>B. pyogenes</i> remain poorly understood and require further investigations. Indeed, despite common antimicrobial susceptibilities, infections frequently persist and require multiple courses of antibiotics. In addition, based on literature data, this review indicates that treatment of skin and soft tissue infections often necessitates surgical procedures and hospitalization.https://www.mdpi.com/2076-2607/13/6/1200anaerobic infectionanimal bitezoonotic infectionskin and soft tissue infectionMALDI-TOF mass spectrometry identification |
| spellingShingle | Carola Mauri Chiara Giubbi Alessandra Consonni Elena Briozzo Elisa Meroni Francesco Luzzaro Silvia Tonolo The Emergence of <i>Bacteroides pyogenes</i> as a Human Pathogen of Animal Origin: A Narrative Review Microorganisms anaerobic infection animal bite zoonotic infection skin and soft tissue infection MALDI-TOF mass spectrometry identification |
| title | The Emergence of <i>Bacteroides pyogenes</i> as a Human Pathogen of Animal Origin: A Narrative Review |
| title_full | The Emergence of <i>Bacteroides pyogenes</i> as a Human Pathogen of Animal Origin: A Narrative Review |
| title_fullStr | The Emergence of <i>Bacteroides pyogenes</i> as a Human Pathogen of Animal Origin: A Narrative Review |
| title_full_unstemmed | The Emergence of <i>Bacteroides pyogenes</i> as a Human Pathogen of Animal Origin: A Narrative Review |
| title_short | The Emergence of <i>Bacteroides pyogenes</i> as a Human Pathogen of Animal Origin: A Narrative Review |
| title_sort | emergence of i bacteroides pyogenes i as a human pathogen of animal origin a narrative review |
| topic | anaerobic infection animal bite zoonotic infection skin and soft tissue infection MALDI-TOF mass spectrometry identification |
| url | https://www.mdpi.com/2076-2607/13/6/1200 |
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