Three approaches to determining clinically meaningful benefit on the Cohen‐Mansfield Agitation Inventory in dementia clinical trials for agitation

Three approaches to determining clinically meaningful benefit on the Cohen‐Mansfield Agitation Inventory in dementia clinical trials for agitation

Abstract INTRODUCTION There is a need to understand the clinical meaningfulness of symptom score changes in treatment trials of dementia‐related agitation. We estimated minimal clinically important differences (MCIDs) for commonly employed agitation scales and contextualized their clinical applicati...

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Bibliographic Details
Main Authors: Kathy Y. Liu, Chineze Ivenso, Rebecca Howard, Penny Rapaport, Suzanne Reeves, Sube Banerjee, Lon S. Schneider, Maria I. Lapid, Agitation MCID Study Group, Robert Howard
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
agitation
Alzheimer
clinically meaningful benefit
dementia
MCID
trial
Online Access:https://doi.org/10.1002/trc2.70099
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