Diagnostic criteria of metabolic syndrome in children and adolescents
Aim. То investigate the prevalence and the clustering of main metabolic syndrome (MS) components in children and adolescents.Material and methods. In total, 22 children and adolescents (10 girls, 12 boys) aged 4-18 years (mean age 15,09±3,7 years), underwent arterial hypertension (AH) risk factor as...
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| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
2009-04-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1753 |
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| Summary: | Aim. То investigate the prevalence and the clustering of main metabolic syndrome (MS) components in children and adolescents.Material and methods. In total, 22 children and adolescents (10 girls, 12 boys) aged 4-18 years (mean age 15,09±3,7 years), underwent arterial hypertension (AH) risk factor assessment, with exclusion of possible symptomatic AH causes, anthropometry (height, body mass (BM), waist and hops circumference), measurement of total cholesterol (TCH), high an low-density lipoprotein CH (HDL-CH, LDL-CH), triglycerides (TG), leptin, atherogenieity index (AI), Kerdo index, etc.Results. Pregnancy complications, including gestosis, were identified in 36,4% of the MS children’s mothers. MS children and adolescents themselves were characterised by increased BM index (over 90%), AH (90%; mean blood pressure, BP, 143±11/83±12 mm Hg), heart rate of 76-120 bpm (70%), Kerdo index varying from -20,9 to +47,30, which pointed to increased sympathetic tonus, seven-fold increase in leptin level (21,4-185,6 ng/ml), decreased HDL-CH (0,16-1,12 mmol/l), as well as increased LDL-CH (1,48-2,65 mmol/l), TG (1,56±1,85 mmol/l) and IA (2,83±26,06) in 50% ofthe childrenConclusion. Diagnostic criteria of MS in children and adolescents included AH, increased sympathetic tonus, obesity, decreased HDL-CH and increased LDL-CH, TG, leptin and AI. Other MS predictors in children included pregnancy complications and gestosis in their mothers. |
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| ISSN: | 1728-8800 2619-0125 |