The Role of the Skin Microbiome in Pathogenesis of Atopic Dermatitis - Current State of Knowledge
Introduction and purpose The subject of this article is the role of the skin microbiome in the pathogenesis of atopic dermatitis - the current state of knowledge. As is known, the skin plays a key role in protecting the body and maintaining homeostasis, cooperating with the microbiome, which affect...
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Kazimierz Wielki University
2025-06-01
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| Series: | Journal of Education, Health and Sport |
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| Online Access: | https://apcz.umk.pl/JEHS/article/view/60518 |
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| author | Natalia Sidz Monika Brzozowska Wiktoria Wardal Natalia Furlepa Robert Rzenno Karolina Wojciechowska Marcelina Matuszewska Katarzyna Wicha Magdalena Tomaszewska Wiktoria Jedlikowska |
| author_facet | Natalia Sidz Monika Brzozowska Wiktoria Wardal Natalia Furlepa Robert Rzenno Karolina Wojciechowska Marcelina Matuszewska Katarzyna Wicha Magdalena Tomaszewska Wiktoria Jedlikowska |
| author_sort | Natalia Sidz |
| collection | DOAJ |
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Introduction and purpose
The subject of this article is the role of the skin microbiome in the pathogenesis of atopic dermatitis - the current state of knowledge. As is known, the skin plays a key role in protecting the body and maintaining homeostasis, cooperating with the microbiome, which affects its immune functions. The purpose of this article is to provide a comprehensive review of current research on the microbiome's role in the pathogenesis of atopic dermatitis (AD).
Materials and methods
The presented article was developed based on a broad database of peer-reviewed scientific publications obtained from reputable sources such as PubMed, Google Scholar and literature authored by renowned researchers from both Poland and abroad. In the process of analysis and interpretation of information, only scientific publications with a high impact factor were taken into account. The analyses performed include both clinical and experimental studies, as well as systematic reviews and meta-analyses, which allowed for obtaining a comprehensive view of the current state of knowledge in this field.
Description of the state of knowledge
Atopic dermatitis (AD) is a chronic inflammatory disease, the pathogenesis of which is associated with disorders of the skin microbiome, leading to the dominance of pathogenic microorganisms, such as Staphylococcus aureus. Standard methods of treating atopic dermatitis (AD) often bring only short-term relief. Understanding the role of the microbiome in this disease opens the way to new, more effective therapies, such as probiotics and methods supporting the reconstruction of skin microflora, enabling a more personalized therapeutic approach.
Conclusion
The aim of the article is to draw attention to the role of the microbiome in atopic dermatitis (AD), which is currently one of the most common skin diseases. It affects not only children but also adults, influencing their quality of life.
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| format | Article |
| id | doaj-art-4a53798299304af4a4cfec603ba3f355 |
| institution | OA Journals |
| issn | 2391-8306 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj-art-4a53798299304af4a4cfec603ba3f3552025-08-20T02:38:15ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062025-06-018210.12775/JEHS.2025.82.60518The Role of the Skin Microbiome in Pathogenesis of Atopic Dermatitis - Current State of KnowledgeNatalia Sidz0https://orcid.org/0009-0005-0685-4175Monika Brzozowska1https://orcid.org/0009-0006-5574-0059Wiktoria Wardal2https://orcid.org/0009-0008-6665-2374Natalia Furlepa 3https://orcid.org/0009-0002-8163-2087Robert Rzenno4https://orcid.org/0009-0003-3838-3262Karolina Wojciechowska5https://orcid.org/0009-0004-4535-0327Marcelina Matuszewska 6https://orcid.org/0009-0002-2301-669XKatarzyna Wicha7https://orcid.org/0000-0001-8822-2182Magdalena Tomaszewska8https://orcid.org/0009-0009-4567-394XWiktoria Jedlikowska9https://orcid.org/0009-0002-7874-9911University Clinical Center in Gdansk, Poland 80-952 Gdansk, Debinki 7Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland Jagiellońska 13/15, 85-067 BydgoszczPediatric Hospital in Bielsko-Biała, ul. Sobieskiego 83, 43-300 Bielsko-Biała, PolandSamodzielny Publiczny Zakład Opieki Zdrowotnej w Łukowie: Łuków, Poland, PL 21-400 Łuków, ul. Doktora Andrzeja Rogalińskiego 3Independent Public Health Care Facility in Myślenice Szpitalna 2, 32-400 Myślenice, PolandRegionalny Szpital Specjalistyczny im. dr. Władysława Biegańskiego w Grudziądzu Doktora Ludwika Rydygiera 15/17, 86-300 GrudziądzSamodzielny Publiczny Szpital Kliniczny im. prof. W. Orłowskiego CMKP ul. Czerniakowska 231, 00-416 Warszawa1st Military Clinical Hospital with Polyclinic of Independent Public Health Care Unit in Lublin Aleje Racławickie 23, 20-049 Lublin, PolandUniwersytecki Szpital Kliniczny nr. 1 im Norberta Barlickiego w Łodzi ul. Stefana Kopcińskiego 22, 90-153 ŁódźHeliodor Swiecicki Clinical Hospital, Poznań, Poland Introduction and purpose The subject of this article is the role of the skin microbiome in the pathogenesis of atopic dermatitis - the current state of knowledge. As is known, the skin plays a key role in protecting the body and maintaining homeostasis, cooperating with the microbiome, which affects its immune functions. The purpose of this article is to provide a comprehensive review of current research on the microbiome's role in the pathogenesis of atopic dermatitis (AD). Materials and methods The presented article was developed based on a broad database of peer-reviewed scientific publications obtained from reputable sources such as PubMed, Google Scholar and literature authored by renowned researchers from both Poland and abroad. In the process of analysis and interpretation of information, only scientific publications with a high impact factor were taken into account. The analyses performed include both clinical and experimental studies, as well as systematic reviews and meta-analyses, which allowed for obtaining a comprehensive view of the current state of knowledge in this field. Description of the state of knowledge Atopic dermatitis (AD) is a chronic inflammatory disease, the pathogenesis of which is associated with disorders of the skin microbiome, leading to the dominance of pathogenic microorganisms, such as Staphylococcus aureus. Standard methods of treating atopic dermatitis (AD) often bring only short-term relief. Understanding the role of the microbiome in this disease opens the way to new, more effective therapies, such as probiotics and methods supporting the reconstruction of skin microflora, enabling a more personalized therapeutic approach. Conclusion The aim of the article is to draw attention to the role of the microbiome in atopic dermatitis (AD), which is currently one of the most common skin diseases. It affects not only children but also adults, influencing their quality of life. https://apcz.umk.pl/JEHS/article/view/60518skinmicrobiomeatopic dermatitisdysbiosisatopic dermatitis treatmentpersonalized therapy |
| spellingShingle | Natalia Sidz Monika Brzozowska Wiktoria Wardal Natalia Furlepa Robert Rzenno Karolina Wojciechowska Marcelina Matuszewska Katarzyna Wicha Magdalena Tomaszewska Wiktoria Jedlikowska The Role of the Skin Microbiome in Pathogenesis of Atopic Dermatitis - Current State of Knowledge Journal of Education, Health and Sport skin microbiome atopic dermatitis dysbiosis atopic dermatitis treatment personalized therapy |
| title | The Role of the Skin Microbiome in Pathogenesis of Atopic Dermatitis - Current State of Knowledge |
| title_full | The Role of the Skin Microbiome in Pathogenesis of Atopic Dermatitis - Current State of Knowledge |
| title_fullStr | The Role of the Skin Microbiome in Pathogenesis of Atopic Dermatitis - Current State of Knowledge |
| title_full_unstemmed | The Role of the Skin Microbiome in Pathogenesis of Atopic Dermatitis - Current State of Knowledge |
| title_short | The Role of the Skin Microbiome in Pathogenesis of Atopic Dermatitis - Current State of Knowledge |
| title_sort | role of the skin microbiome in pathogenesis of atopic dermatitis current state of knowledge |
| topic | skin microbiome atopic dermatitis dysbiosis atopic dermatitis treatment personalized therapy |
| url | https://apcz.umk.pl/JEHS/article/view/60518 |
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