Evaluation of rheumatologists’ knowledge of biosimilars

Abstract Introduction Biosimilars reduce the cost of biologic therapy without compromising safety and effectiveness. In this study we evaluated Brazilian rheumatologists’ knowledge and perceptions of biosimilars. Methods Cross-sectional and descriptive study based on a questionnaire containing 17 it...

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Main Authors: Thayane Furtado Rolim Lima, Lia Poti Gomes Cordeiro, Kirla Wagner Poti Gomes, Carlos Ewerton Maia Rodrigues
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Advances in Rheumatology
Subjects:
Online Access:https://doi.org/10.1186/s42358-025-00465-4
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author Thayane Furtado Rolim Lima
Lia Poti Gomes Cordeiro
Kirla Wagner Poti Gomes
Carlos Ewerton Maia Rodrigues
author_facet Thayane Furtado Rolim Lima
Lia Poti Gomes Cordeiro
Kirla Wagner Poti Gomes
Carlos Ewerton Maia Rodrigues
author_sort Thayane Furtado Rolim Lima
collection DOAJ
description Abstract Introduction Biosimilars reduce the cost of biologic therapy without compromising safety and effectiveness. In this study we evaluated Brazilian rheumatologists’ knowledge and perceptions of biosimilars. Methods Cross-sectional and descriptive study based on a questionnaire containing 17 items on familiarity, knowledge and perceptions of biosimilars. Results Answers were received from 135 rheumatologists, of whom 97.8% were familiar with biosimilars and 92.5% had at some time prescribed them, but only 47.7% felt comfortable prescribing them to stable patients and 62.2% strongly disagreed with automatic substitution. In addition, 51.9% preferred naive patients when starting treatment with biosimilars. Conclusion Despite the growing acceptance of biosimilars, many physicians remain reluctant. Evidence-based continuing education is essential to clarify these issues.
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series Advances in Rheumatology
spelling doaj-art-4a44f1120bcd4270b44da080f03c1ce72025-08-20T03:42:04ZengBMCAdvances in Rheumatology2523-31062025-07-016511710.1186/s42358-025-00465-4Evaluation of rheumatologists’ knowledge of biosimilarsThayane Furtado Rolim Lima0Lia Poti Gomes Cordeiro1Kirla Wagner Poti Gomes2Carlos Ewerton Maia Rodrigues3Resident in Rheumatology, General Hospital of Fortaleza (HGF)Resident in Internal Medicine, Waldemar Alcântara General Hospital (HGWA)Health Sciences from University of Fortaleza (Unifor), General Hospital of Fortaleza (HGF)Graduate Program in Medical Sciences, Universidade de Fortaleza (Unifor)Abstract Introduction Biosimilars reduce the cost of biologic therapy without compromising safety and effectiveness. In this study we evaluated Brazilian rheumatologists’ knowledge and perceptions of biosimilars. Methods Cross-sectional and descriptive study based on a questionnaire containing 17 items on familiarity, knowledge and perceptions of biosimilars. Results Answers were received from 135 rheumatologists, of whom 97.8% were familiar with biosimilars and 92.5% had at some time prescribed them, but only 47.7% felt comfortable prescribing them to stable patients and 62.2% strongly disagreed with automatic substitution. In addition, 51.9% preferred naive patients when starting treatment with biosimilars. Conclusion Despite the growing acceptance of biosimilars, many physicians remain reluctant. Evidence-based continuing education is essential to clarify these issues.https://doi.org/10.1186/s42358-025-00465-4BiosimilarsBiosimilar drugsInterchangeabilityExtrapolation
spellingShingle Thayane Furtado Rolim Lima
Lia Poti Gomes Cordeiro
Kirla Wagner Poti Gomes
Carlos Ewerton Maia Rodrigues
Evaluation of rheumatologists’ knowledge of biosimilars
Advances in Rheumatology
Biosimilars
Biosimilar drugs
Interchangeability
Extrapolation
title Evaluation of rheumatologists’ knowledge of biosimilars
title_full Evaluation of rheumatologists’ knowledge of biosimilars
title_fullStr Evaluation of rheumatologists’ knowledge of biosimilars
title_full_unstemmed Evaluation of rheumatologists’ knowledge of biosimilars
title_short Evaluation of rheumatologists’ knowledge of biosimilars
title_sort evaluation of rheumatologists knowledge of biosimilars
topic Biosimilars
Biosimilar drugs
Interchangeability
Extrapolation
url https://doi.org/10.1186/s42358-025-00465-4
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