Comparison of Modified Ferriman-Gallwey Score and Biochemical Parameters in the Estimation of the Prevalence of Idiopathic Hirsutism Among Women in the Kurdistan Region

The word "hirsutism" describes the development of terminal hairs at androgen-controlled body locations in women, which has distress and adverse psychosocial affects. The diagnosis of hirsutism is the key point in the treatment of unwanted hair growth in women’s body. Present study aimed to...

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Main Authors: Bushra Maree jarallah, Hataw Adil, Ayad Palani
Format: Article
Language:English
Published: College of Medicine, Al-Nahrain University 2023-09-01
Series:Baghdad Journal of Biochemistry and Applied Biological Sciences
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Online Access:https://bjbabs.org/index.php/bjbabs/article/view/259
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author Bushra Maree jarallah
Hataw Adil
Ayad Palani
author_facet Bushra Maree jarallah
Hataw Adil
Ayad Palani
author_sort Bushra Maree jarallah
collection DOAJ
description The word "hirsutism" describes the development of terminal hairs at androgen-controlled body locations in women, which has distress and adverse psychosocial affects. The diagnosis of hirsutism is the key point in the treatment of unwanted hair growth in women’s body. Present study aimed to evaluate the modified Ferriman-Gallwey (mFG) score and the biochemical hyperandrogenism parameters among Iraqi hirsute women and their association with hirsutism in outpatients clinics in Kalar city, Garmian region, Iraq. This was a cross-sectional study of 100 hirsute women were collected from the outpatients clinic and 26 healthy women in Kalar city. After detailed history taking by using structured questionnaire, physical examination, and the relevant investigations were done, the scoring of hirsutism was indexed according to (mFG) scoring system. Moreover, sera of hormonal markers were measured; which included 17-hydroxyprogesterone (17-OHP), total testosterone (TT), free testosterone (FT), dehydroepiandrosterone (DHEA), s. prolactin, and thyroid stimulating hormone (TSH). No statistically significant differences were found in the median of the sex and related hormones between control subjects and the hirsutism group. Likewise, there were no significant relation between hormonal markers and the rate of hirsutism. While, an intrinsic statistical association was seen between the mFG score with the hirsutism and the rate of hirsutism. Our findings imply that the mFG score system is a significance screening tool and has tremendous importance and utility in establishing the diagnosis of hirsutism.
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spelling doaj-art-4a440ebdd1bd4153847fe4d1260efba42025-08-20T03:22:14ZengCollege of Medicine, Al-Nahrain UniversityBaghdad Journal of Biochemistry and Applied Biological Sciences2706-99152023-09-014311512310.47419/bjbabs.v4i03.259Comparison of Modified Ferriman-Gallwey Score and Biochemical Parameters in the Estimation of the Prevalence of Idiopathic Hirsutism Among Women in the Kurdistan RegionBushra Maree jarallah0Hataw Adil1https://orcid.org/0000-0003-1181-3720Ayad Palani2https://orcid.org/0000-0001-7806-9903College of Medicine, University of Garmian, Kalar, Kurdistan region, IraqDepartment of Chemistry, College of Education, University of Garmian, Kalar, Kurdistan region, IraqCollege of Medicine, University of Garmian, Kalar, Kurdistan region, IraqThe word "hirsutism" describes the development of terminal hairs at androgen-controlled body locations in women, which has distress and adverse psychosocial affects. The diagnosis of hirsutism is the key point in the treatment of unwanted hair growth in women’s body. Present study aimed to evaluate the modified Ferriman-Gallwey (mFG) score and the biochemical hyperandrogenism parameters among Iraqi hirsute women and their association with hirsutism in outpatients clinics in Kalar city, Garmian region, Iraq. This was a cross-sectional study of 100 hirsute women were collected from the outpatients clinic and 26 healthy women in Kalar city. After detailed history taking by using structured questionnaire, physical examination, and the relevant investigations were done, the scoring of hirsutism was indexed according to (mFG) scoring system. Moreover, sera of hormonal markers were measured; which included 17-hydroxyprogesterone (17-OHP), total testosterone (TT), free testosterone (FT), dehydroepiandrosterone (DHEA), s. prolactin, and thyroid stimulating hormone (TSH). No statistically significant differences were found in the median of the sex and related hormones between control subjects and the hirsutism group. Likewise, there were no significant relation between hormonal markers and the rate of hirsutism. While, an intrinsic statistical association was seen between the mFG score with the hirsutism and the rate of hirsutism. Our findings imply that the mFG score system is a significance screening tool and has tremendous importance and utility in establishing the diagnosis of hirsutism.https://bjbabs.org/index.php/bjbabs/article/view/259hirsutismsex hormonespcosandrogensprevalenceetiologyhyperandrogenismmodified ferriman-gallwey
spellingShingle Bushra Maree jarallah
Hataw Adil
Ayad Palani
Comparison of Modified Ferriman-Gallwey Score and Biochemical Parameters in the Estimation of the Prevalence of Idiopathic Hirsutism Among Women in the Kurdistan Region
Baghdad Journal of Biochemistry and Applied Biological Sciences
hirsutism
sex hormones
pcos
androgens
prevalence
etiology
hyperandrogenism
modified ferriman-gallwey
title Comparison of Modified Ferriman-Gallwey Score and Biochemical Parameters in the Estimation of the Prevalence of Idiopathic Hirsutism Among Women in the Kurdistan Region
title_full Comparison of Modified Ferriman-Gallwey Score and Biochemical Parameters in the Estimation of the Prevalence of Idiopathic Hirsutism Among Women in the Kurdistan Region
title_fullStr Comparison of Modified Ferriman-Gallwey Score and Biochemical Parameters in the Estimation of the Prevalence of Idiopathic Hirsutism Among Women in the Kurdistan Region
title_full_unstemmed Comparison of Modified Ferriman-Gallwey Score and Biochemical Parameters in the Estimation of the Prevalence of Idiopathic Hirsutism Among Women in the Kurdistan Region
title_short Comparison of Modified Ferriman-Gallwey Score and Biochemical Parameters in the Estimation of the Prevalence of Idiopathic Hirsutism Among Women in the Kurdistan Region
title_sort comparison of modified ferriman gallwey score and biochemical parameters in the estimation of the prevalence of idiopathic hirsutism among women in the kurdistan region
topic hirsutism
sex hormones
pcos
androgens
prevalence
etiology
hyperandrogenism
modified ferriman-gallwey
url https://bjbabs.org/index.php/bjbabs/article/view/259
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AT ayadpalani comparisonofmodifiedferrimangallweyscoreandbiochemicalparametersintheestimationoftheprevalenceofidiopathichirsutismamongwomeninthekurdistanregion