Pleiotropic effects of PPAR-α – from benchside to bedside

Pleiotropic effects of PPAR-α – from benchside to bedside

Here we review literature data on properties of a member of nuclear hormone receptors - peroxisome proliferator-activated receptor-α. It was shown that PPARα was expressed on different cells including dendritic cells, macrophages, B- and T-cells. We discuss structure of natural and synthetic ligands...

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Bibliographic Details
Main Authors: I. V. Shirinsky, V. S. Shirinsky
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2021-06-01
Series:Медицинская иммунология
Subjects:
pparα
metabolism
lipids
glucose
inflammation
pleiotropic
fenofibrate
phagocytes
lymphocytes
Online Access:https://www.mimmun.ru/mimmun/article/view/2222
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