Co-Inactivation of GlnR and CodY Regulators Impacts Pneumococcal Cell Wall Physiology.
CodY, a nutritional regulator highly conserved in low G+C Gram-positive bacteria, is essential in Streptococcus pneumoniae (the pneumococcus). A published codY mutant possessed suppressing mutations inactivating the fatC and amiC genes, respectively belonging to iron (Fat/Fec) and oligopeptide (Ami)...
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| Main Authors: | Calum Johnston, Hester J Bootsma, Christine Aldridge, Sylvie Manuse, Nicolas Gisch, Dominik Schwudke, Peter W M Hermans, Christophe Grangeasse, Patrice Polard, Waldemar Vollmer, Jean-Pierre Claverys |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0123702 |
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