Co-Inactivation of GlnR and CodY Regulators Impacts Pneumococcal Cell Wall Physiology.

Co-Inactivation of GlnR and CodY Regulators Impacts Pneumococcal Cell Wall Physiology.

CodY, a nutritional regulator highly conserved in low G+C Gram-positive bacteria, is essential in Streptococcus pneumoniae (the pneumococcus). A published codY mutant possessed suppressing mutations inactivating the fatC and amiC genes, respectively belonging to iron (Fat/Fec) and oligopeptide (Ami)...

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Main Authors: Calum Johnston, Hester J Bootsma, Christine Aldridge, Sylvie Manuse, Nicolas Gisch, Dominik Schwudke, Peter W M Hermans, Christophe Grangeasse, Patrice Polard, Waldemar Vollmer, Jean-Pierre Claverys
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0123702
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https://doi.org/10.1371/journal.pone.0123702

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