The association between the duration of surgery and risks of mortality and unplanned reoperation is modulated by the surgical start time

Abstract To evaluate the associations of neurosurgical start and duration with surgical outcomes. This retrospective study analysed elective neurosurgery data from January 1, 2017, to December 30, 2021. Unplanned reoperation and postoperative mortality during hospitalization were the outcomes. We di...

Full description

Saved in:
Bibliographic Details
Main Authors: Zilong Mao, Jinan Zhang, Peng Wang, Wei Zuo
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-12265-3
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849234611015516160
author Zilong Mao
Jinan Zhang
Peng Wang
Wei Zuo
author_facet Zilong Mao
Jinan Zhang
Peng Wang
Wei Zuo
author_sort Zilong Mao
collection DOAJ
description Abstract To evaluate the associations of neurosurgical start and duration with surgical outcomes. This retrospective study analysed elective neurosurgery data from January 1, 2017, to December 30, 2021. Unplanned reoperation and postoperative mortality during hospitalization were the outcomes. We divided the surgical start time, duration and completion time into categories (Q1: 8–13:00; Q2:13–17:00; and Q3: others), (Q1: less than 5 h; Q2: 5–10 h; and Q3: others), and (Q1: 08–18:00; and Q2: others). Generalized linear mixed models were used to explore associations between surgical time subgroups and outcomes. Interaction analyses were performed to evaluate surgical outcomes and subgroup interaction associations. In total, 16,549 patients were analysed, and 611 patients had adverse outcomes. Compared with earlier start times and shorter durations, later start times and longer durations were associated with 200 and 600% greater risks, respectively. Compared with earlier and longer-duration surgeries, earlier and longer-duration surgeries were associated with a lower risk of adverse events. These data indicate that a later surgical time and longer duration are associated with more adverse surgical results. Furthermore, the association between the duration of the operation and surgical outcomes might be modulated by the surgical start time.
format Article
id doaj-art-4a23f05b679d41eab96f768db5ea4605
institution Kabale University
issn 2045-2322
language English
publishDate 2025-08-01
publisher Nature Portfolio
record_format Article
series Scientific Reports
spelling doaj-art-4a23f05b679d41eab96f768db5ea46052025-08-20T04:03:06ZengNature PortfolioScientific Reports2045-23222025-08-011511910.1038/s41598-025-12265-3The association between the duration of surgery and risks of mortality and unplanned reoperation is modulated by the surgical start timeZilong Mao0Jinan Zhang1Peng Wang2Wei Zuo3Department of Spine Surgery, Xi’an No 3. Hospital, The Affiliated Hospital of Northwest UniversityDepartment of Neurosurgery, Tangdu Hospital Affiliated Air Force Medical UniversityDepartment of Neurosurgery, Tangdu Hospital Affiliated Air Force Medical UniversityDepartment of Spine Surgery, Xi’an No 3. Hospital, The Affiliated Hospital of Northwest UniversityAbstract To evaluate the associations of neurosurgical start and duration with surgical outcomes. This retrospective study analysed elective neurosurgery data from January 1, 2017, to December 30, 2021. Unplanned reoperation and postoperative mortality during hospitalization were the outcomes. We divided the surgical start time, duration and completion time into categories (Q1: 8–13:00; Q2:13–17:00; and Q3: others), (Q1: less than 5 h; Q2: 5–10 h; and Q3: others), and (Q1: 08–18:00; and Q2: others). Generalized linear mixed models were used to explore associations between surgical time subgroups and outcomes. Interaction analyses were performed to evaluate surgical outcomes and subgroup interaction associations. In total, 16,549 patients were analysed, and 611 patients had adverse outcomes. Compared with earlier start times and shorter durations, later start times and longer durations were associated with 200 and 600% greater risks, respectively. Compared with earlier and longer-duration surgeries, earlier and longer-duration surgeries were associated with a lower risk of adverse events. These data indicate that a later surgical time and longer duration are associated with more adverse surgical results. Furthermore, the association between the duration of the operation and surgical outcomes might be modulated by the surgical start time.https://doi.org/10.1038/s41598-025-12265-3Unplanned reoperationMortalitySurgical start timeOperative durationFatigue
spellingShingle Zilong Mao
Jinan Zhang
Peng Wang
Wei Zuo
The association between the duration of surgery and risks of mortality and unplanned reoperation is modulated by the surgical start time
Scientific Reports
Unplanned reoperation
Mortality
Surgical start time
Operative duration
Fatigue
title The association between the duration of surgery and risks of mortality and unplanned reoperation is modulated by the surgical start time
title_full The association between the duration of surgery and risks of mortality and unplanned reoperation is modulated by the surgical start time
title_fullStr The association between the duration of surgery and risks of mortality and unplanned reoperation is modulated by the surgical start time
title_full_unstemmed The association between the duration of surgery and risks of mortality and unplanned reoperation is modulated by the surgical start time
title_short The association between the duration of surgery and risks of mortality and unplanned reoperation is modulated by the surgical start time
title_sort association between the duration of surgery and risks of mortality and unplanned reoperation is modulated by the surgical start time
topic Unplanned reoperation
Mortality
Surgical start time
Operative duration
Fatigue
url https://doi.org/10.1038/s41598-025-12265-3
work_keys_str_mv AT zilongmao theassociationbetweenthedurationofsurgeryandrisksofmortalityandunplannedreoperationismodulatedbythesurgicalstarttime
AT jinanzhang theassociationbetweenthedurationofsurgeryandrisksofmortalityandunplannedreoperationismodulatedbythesurgicalstarttime
AT pengwang theassociationbetweenthedurationofsurgeryandrisksofmortalityandunplannedreoperationismodulatedbythesurgicalstarttime
AT weizuo theassociationbetweenthedurationofsurgeryandrisksofmortalityandunplannedreoperationismodulatedbythesurgicalstarttime
AT zilongmao associationbetweenthedurationofsurgeryandrisksofmortalityandunplannedreoperationismodulatedbythesurgicalstarttime
AT jinanzhang associationbetweenthedurationofsurgeryandrisksofmortalityandunplannedreoperationismodulatedbythesurgicalstarttime
AT pengwang associationbetweenthedurationofsurgeryandrisksofmortalityandunplannedreoperationismodulatedbythesurgicalstarttime
AT weizuo associationbetweenthedurationofsurgeryandrisksofmortalityandunplannedreoperationismodulatedbythesurgicalstarttime