Transduction of SIV-specific TCR genes into rhesus macaque CD8+ T cells conveys the ability to suppress SIV replication.

Transduction of SIV-specific TCR genes into rhesus macaque CD8+ T cells conveys the ability to suppress SIV replication.

<h4>Background</h4>The SIV/rhesus macaque model for HIV/AIDS is a powerful system for examining the contribution of T cells in the control of AIDS viruses. To better our understanding of CD8(+) T-cell control of SIV replication in CD4(+) T cells, we asked whether TCRs isolated from rhesu...

Full description

Saved in:
Bibliographic Details
Main Authors: Eugene V Barsov, Matthew T Trivett, Jacob T Minang, Haosi Sun, Claes Ohlen, David E Ott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023703&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items