Clinical Effects of Amoxicillin-clavulanate and Calcium Hydroxide as Intracanal Medicament on Inter appointment Pain among Symptomatic Apical Periodontitis

ABSTRACT Objective: To compare the clinical effects of Antibiotic amoxicillin-clavulanate and calcium hydroxide on inter appointment pain in cases of Symptomatic Apical Periodontitis. Methodology: It was a single blind randomized controlled trial study performed in operative Dentistry Department of...

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Main Authors: Naresh Kumar, Rajesh Kumar, Priya Harjani, Sarang Suresh
Format: Article
Language:English
Published: Bahria Univerisy Health Sciences, Campus Karachi 2021-10-01
Series:Journal of Bahria University Medical and Dental College
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Online Access:https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/713
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author Naresh Kumar
Rajesh Kumar
Priya Harjani
Sarang Suresh
author_facet Naresh Kumar
Rajesh Kumar
Priya Harjani
Sarang Suresh
author_sort Naresh Kumar
collection DOAJ
description ABSTRACT Objective: To compare the clinical effects of Antibiotic amoxicillin-clavulanate and calcium hydroxide on inter appointment pain in cases of Symptomatic Apical Periodontitis. Methodology: It was a single blind randomized controlled trial study performed in operative Dentistry Department of Liaquat University of Medical and Health Sciences Jamshoro. This study was conducted from 02-Jan-2017 to 27-June- 2017. Total n=324 patients with symptomatic apical periodontitis were targeted. Patients were randomly allocated into two groups. Total n=162 patients in group1 treated with Antibiotic amoxicillin-clavulanate and n=162 patients in group 2 of calcium hydroxide. Procedure was performed by single operator. Clinical effect was assessed if pain present or absent after 24 hours and 7 days on recalled visit and was labeled as positive when there was no pain (0-3 on VAS) and as negative when there was pain (4-10 on VAS). Data of the study was analyzed by using the SPSS version 20. Mean and standard deviation was calculated for quantitative variables like age and pre and postoperative pain. Frequency and percentages were calculated for type of tooth. Both groups were compared by using Chi- square test for clinical effect. Results: The average age of the patients was 39.807.36 years. There were 50% male and 50% female. Clinical effectiveness was significantly high in group 1 than group 2 [79.01% vs. 65.43% p=0.006]. Conclusion: The findings of this study are encouraging that patients in which Amoxicillin-clavulanate was used as intracanal medicament appeared to show a greater decrease in pain levels over the observation period when compared to the control group.
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spelling doaj-art-4a1af459ce50498eae576a68d07664282025-08-20T02:15:46ZengBahria Univerisy Health Sciences, Campus KarachiJournal of Bahria University Medical and Dental College2220-75622617-94822021-10-0111410.51985/JBUMDC2021047Clinical Effects of Amoxicillin-clavulanate and Calcium Hydroxide as Intracanal Medicament on Inter appointment Pain among Symptomatic Apical PeriodontitisNaresh KumarRajesh KumarPriya HarjaniSarang Suresh ABSTRACT Objective: To compare the clinical effects of Antibiotic amoxicillin-clavulanate and calcium hydroxide on inter appointment pain in cases of Symptomatic Apical Periodontitis. Methodology: It was a single blind randomized controlled trial study performed in operative Dentistry Department of Liaquat University of Medical and Health Sciences Jamshoro. This study was conducted from 02-Jan-2017 to 27-June- 2017. Total n=324 patients with symptomatic apical periodontitis were targeted. Patients were randomly allocated into two groups. Total n=162 patients in group1 treated with Antibiotic amoxicillin-clavulanate and n=162 patients in group 2 of calcium hydroxide. Procedure was performed by single operator. Clinical effect was assessed if pain present or absent after 24 hours and 7 days on recalled visit and was labeled as positive when there was no pain (0-3 on VAS) and as negative when there was pain (4-10 on VAS). Data of the study was analyzed by using the SPSS version 20. Mean and standard deviation was calculated for quantitative variables like age and pre and postoperative pain. Frequency and percentages were calculated for type of tooth. Both groups were compared by using Chi- square test for clinical effect. Results: The average age of the patients was 39.807.36 years. There were 50% male and 50% female. Clinical effectiveness was significantly high in group 1 than group 2 [79.01% vs. 65.43% p=0.006]. Conclusion: The findings of this study are encouraging that patients in which Amoxicillin-clavulanate was used as intracanal medicament appeared to show a greater decrease in pain levels over the observation period when compared to the control group. https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/713Amoxicillin-clavulanate, Calcium Hydroxide, Flareup, Pain, Symptomatic Apical Periodontitis
spellingShingle Naresh Kumar
Rajesh Kumar
Priya Harjani
Sarang Suresh
Clinical Effects of Amoxicillin-clavulanate and Calcium Hydroxide as Intracanal Medicament on Inter appointment Pain among Symptomatic Apical Periodontitis
Journal of Bahria University Medical and Dental College
Amoxicillin-clavulanate, Calcium Hydroxide, Flareup, Pain, Symptomatic Apical Periodontitis
title Clinical Effects of Amoxicillin-clavulanate and Calcium Hydroxide as Intracanal Medicament on Inter appointment Pain among Symptomatic Apical Periodontitis
title_full Clinical Effects of Amoxicillin-clavulanate and Calcium Hydroxide as Intracanal Medicament on Inter appointment Pain among Symptomatic Apical Periodontitis
title_fullStr Clinical Effects of Amoxicillin-clavulanate and Calcium Hydroxide as Intracanal Medicament on Inter appointment Pain among Symptomatic Apical Periodontitis
title_full_unstemmed Clinical Effects of Amoxicillin-clavulanate and Calcium Hydroxide as Intracanal Medicament on Inter appointment Pain among Symptomatic Apical Periodontitis
title_short Clinical Effects of Amoxicillin-clavulanate and Calcium Hydroxide as Intracanal Medicament on Inter appointment Pain among Symptomatic Apical Periodontitis
title_sort clinical effects of amoxicillin clavulanate and calcium hydroxide as intracanal medicament on inter appointment pain among symptomatic apical periodontitis
topic Amoxicillin-clavulanate, Calcium Hydroxide, Flareup, Pain, Symptomatic Apical Periodontitis
url https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/713
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