Sildenafil Citrate Influences Production of TNF-α in Healthy Men Lymphocytes

Sildenafil Citrate Influences Production of TNF-α in Healthy Men Lymphocytes

The aim of our study was to determine whether sildenafil citrate influences the production of Th1- (TNF-α, INF-γ) or Th2-type (TGF-β, IL-10) cytokines by lymphocytes of healthy men. Sildenafil citrate (SC) is a selective blocker of phosphodiesterase 5, by competing for the binding site with cGMP. It...

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Bibliographic Details
Main Authors:	Michał Zych, Aleksander Roszczyk, Monika Kniotek, Beata Kaleta, Radoslaw Zagozdzon
Format:	Article
Language:	English
Published:	Wiley 2019-01-01
Series:	Journal of Immunology Research
Online Access:	http://dx.doi.org/10.1155/2019/8478750
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