A Correlation of Alarin with Some Anthropometric Measurements in Iraqi Type II Diabetic Patients
Background: Diabetes mellitus (DM) is a group of chronic metabolic diseases that affect the body’s ability to produce insulin. It is one of the most common endocrine disorders. Objectives: This study aims to measure whether there was any association between alarin and some anthropometric measurement...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Medical Journal of Babylon |
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| Online Access: | https://doi.org/10.4103/MJBL.MJBL_835_23 |
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| author | Russell S. A. Al-Shaabani Shakir F. T. Alaaraj |
| author_facet | Russell S. A. Al-Shaabani Shakir F. T. Alaaraj |
| author_sort | Russell S. A. Al-Shaabani |
| collection | DOAJ |
| description | Background: Diabetes mellitus (DM) is a group of chronic metabolic diseases that affect the body’s ability to produce insulin. It is one of the most common endocrine disorders. Objectives: This study aims to measure whether there was any association between alarin and some anthropometric measurements (AMs) such as waist/nick (W/N), waist/thoracic (W/T), waist/hip (W/H) in Iraqi type II diabetic patients. Materials and Methods: This study included 43 patients from Ramadi Teaching Hospitals, in addition to 43 healthy controls. Enzyme-linked immunosorbent assay was used to determine serum alarin level, while the fasting serum glucose (FSG) level was determined by enzymatic colorimetric methods. Results: Serum alarin (ng/mL) was higher in DM patients than in HCs (P < 0.0001), body mass index (BMI) was significantly higher in patients with T2DM, in addition, FSG) mg/dL (was higher in T2DM than HCs. Furthermore, alarin was positively associated with BMI (0.151), W/H (0.006), W/T (0.008), W/N (0.1260), and FSG (0.612). The receiver operating characteristic (ROC) curve indicates that alarin and FSG were excellent sensitive markers in the diagnosis of T2DM. Moreover, ROC indicated that W/N gave good sensitive signs. New values of the cutoff value for studied variables have been estimated as follows: alarin (>2.035 ng/mL), W/H (>0.9554), W/T (>0.9633), W/N (>2.665), H/T (>1.06), and FSG (>116.5 mg/dL). Conclusion: A very weak correlation appeared for alarin with AMs; the serum level of alarin was higher in T2DM than HCS; this means alarin may be used as a novel biomarker in the detection of T2DM and may be an effective biomarker in the diagnostic test for the disease. |
| format | Article |
| id | doaj-art-4a08a99ab39a404fba488bfa8186b7de |
| institution | Kabale University |
| issn | 1812-156X 2312-6760 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Babylon |
| spelling | doaj-art-4a08a99ab39a404fba488bfa8186b7de2025-01-17T10:54:56ZengWolters Kluwer Medknow PublicationsMedical Journal of Babylon1812-156X2312-67602024-12-012141027103010.4103/MJBL.MJBL_835_23A Correlation of Alarin with Some Anthropometric Measurements in Iraqi Type II Diabetic PatientsRussell S. A. Al-ShaabaniShakir F. T. AlaarajBackground: Diabetes mellitus (DM) is a group of chronic metabolic diseases that affect the body’s ability to produce insulin. It is one of the most common endocrine disorders. Objectives: This study aims to measure whether there was any association between alarin and some anthropometric measurements (AMs) such as waist/nick (W/N), waist/thoracic (W/T), waist/hip (W/H) in Iraqi type II diabetic patients. Materials and Methods: This study included 43 patients from Ramadi Teaching Hospitals, in addition to 43 healthy controls. Enzyme-linked immunosorbent assay was used to determine serum alarin level, while the fasting serum glucose (FSG) level was determined by enzymatic colorimetric methods. Results: Serum alarin (ng/mL) was higher in DM patients than in HCs (P < 0.0001), body mass index (BMI) was significantly higher in patients with T2DM, in addition, FSG) mg/dL (was higher in T2DM than HCs. Furthermore, alarin was positively associated with BMI (0.151), W/H (0.006), W/T (0.008), W/N (0.1260), and FSG (0.612). The receiver operating characteristic (ROC) curve indicates that alarin and FSG were excellent sensitive markers in the diagnosis of T2DM. Moreover, ROC indicated that W/N gave good sensitive signs. New values of the cutoff value for studied variables have been estimated as follows: alarin (>2.035 ng/mL), W/H (>0.9554), W/T (>0.9633), W/N (>2.665), H/T (>1.06), and FSG (>116.5 mg/dL). Conclusion: A very weak correlation appeared for alarin with AMs; the serum level of alarin was higher in T2DM than HCS; this means alarin may be used as a novel biomarker in the detection of T2DM and may be an effective biomarker in the diagnostic test for the disease.https://doi.org/10.4103/MJBL.MJBL_835_23alarinfasting serum glucosewaist/hipwaist/thoracic |
| spellingShingle | Russell S. A. Al-Shaabani Shakir F. T. Alaaraj A Correlation of Alarin with Some Anthropometric Measurements in Iraqi Type II Diabetic Patients Medical Journal of Babylon alarin fasting serum glucose waist/hip waist/thoracic |
| title | A Correlation of Alarin with Some Anthropometric Measurements in Iraqi Type II Diabetic Patients |
| title_full | A Correlation of Alarin with Some Anthropometric Measurements in Iraqi Type II Diabetic Patients |
| title_fullStr | A Correlation of Alarin with Some Anthropometric Measurements in Iraqi Type II Diabetic Patients |
| title_full_unstemmed | A Correlation of Alarin with Some Anthropometric Measurements in Iraqi Type II Diabetic Patients |
| title_short | A Correlation of Alarin with Some Anthropometric Measurements in Iraqi Type II Diabetic Patients |
| title_sort | correlation of alarin with some anthropometric measurements in iraqi type ii diabetic patients |
| topic | alarin fasting serum glucose waist/hip waist/thoracic |
| url | https://doi.org/10.4103/MJBL.MJBL_835_23 |
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