Acute kidney injury among hospitalised patients who died due to COVID-19 in the Eastern Cape, South Africa
Background: Acute kidney injury (AKI) commonly occurs in coronavirus disease 2019 (COVID-19) patients who have been hospitalised and is associated with a poor prognosis. This study aimed to determine the incidence of AKI among COVID-19 patients who died in a regional hospital in South Africa. Metho...
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AOSIS
2023-01-01
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| Series: | South African Family Practice |
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| Online Access: | https://safpj.co.za/index.php/safpj/article/view/5616 |
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| author | Ramprakash Kaswa |
| author_facet | Ramprakash Kaswa |
| author_sort | Ramprakash Kaswa |
| collection | DOAJ |
| description | Background: Acute kidney injury (AKI) commonly occurs in coronavirus disease 2019 (COVID-19) patients who have been hospitalised and is associated with a poor prognosis. This study aimed to determine the incidence of AKI among COVID-19 patients who died in a regional hospital in South Africa.
Methods: This retrospective record review was conducted at the Mthatha Regional Hospital in South Africa’s Eastern Cape province. Data were collected between 10 July 2020 and 31 January 2021.
Results: The incidence of AKI was 38% among the hospitalised patients who died due to COVID-19. Most study participants were female, with a mean age of 63.3 ± 16 years. The most common symptom of COVID-19 at the time of hospitalisation was shortness of breath, followed by fever and cough. Half of the patients had hypertension, while diabetes, human immunodeficiency viruses (HIV) and tuberculosis (TB) were other comorbidities. At admission, the average oxygen saturation was 75.5% ± 17.
Conclusion: The study revealed a high incidence of AKI among hospitalised patients who died due to COVID-19. It also found that those received adequate crystalloid fluids at the time of admission had a lower incidence of AKI.
Contribution: Acute kidney injury can be prevented by adequate fluid management during early stage of COVID-19. Majority of COVID-19 patients were referred from lower level of care and primary care providers have their first encounter with these patients. Adequate fluid resuscitation in primary care settings can improve the outcome of hospitalised COVID-19 patients. |
| format | Article |
| id | doaj-art-4a07c6e7b31a41a7b2eb3c7ef33d5434 |
| institution | DOAJ |
| issn | 2078-6190 2078-6204 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | AOSIS |
| record_format | Article |
| series | South African Family Practice |
| spelling | doaj-art-4a07c6e7b31a41a7b2eb3c7ef33d54342025-08-20T03:06:51ZengAOSISSouth African Family Practice2078-61902078-62042023-01-01651e1e510.4102/safp.v65i1.56164299Acute kidney injury among hospitalised patients who died due to COVID-19 in the Eastern Cape, South AfricaRamprakash Kaswa0Department of Family Medicine and Rural Health, Faculty of Health Sciences, Walter Sisulu University, MthathaBackground: Acute kidney injury (AKI) commonly occurs in coronavirus disease 2019 (COVID-19) patients who have been hospitalised and is associated with a poor prognosis. This study aimed to determine the incidence of AKI among COVID-19 patients who died in a regional hospital in South Africa. Methods: This retrospective record review was conducted at the Mthatha Regional Hospital in South Africa’s Eastern Cape province. Data were collected between 10 July 2020 and 31 January 2021. Results: The incidence of AKI was 38% among the hospitalised patients who died due to COVID-19. Most study participants were female, with a mean age of 63.3 ± 16 years. The most common symptom of COVID-19 at the time of hospitalisation was shortness of breath, followed by fever and cough. Half of the patients had hypertension, while diabetes, human immunodeficiency viruses (HIV) and tuberculosis (TB) were other comorbidities. At admission, the average oxygen saturation was 75.5% ± 17. Conclusion: The study revealed a high incidence of AKI among hospitalised patients who died due to COVID-19. It also found that those received adequate crystalloid fluids at the time of admission had a lower incidence of AKI. Contribution: Acute kidney injury can be prevented by adequate fluid management during early stage of COVID-19. Majority of COVID-19 patients were referred from lower level of care and primary care providers have their first encounter with these patients. Adequate fluid resuscitation in primary care settings can improve the outcome of hospitalised COVID-19 patients.https://safpj.co.za/index.php/safpj/article/view/5616akicovid-19hospitalisedcomorbidityprognosis |
| spellingShingle | Ramprakash Kaswa Acute kidney injury among hospitalised patients who died due to COVID-19 in the Eastern Cape, South Africa South African Family Practice aki covid-19 hospitalised comorbidity prognosis |
| title | Acute kidney injury among hospitalised patients who died due to COVID-19 in the Eastern Cape, South Africa |
| title_full | Acute kidney injury among hospitalised patients who died due to COVID-19 in the Eastern Cape, South Africa |
| title_fullStr | Acute kidney injury among hospitalised patients who died due to COVID-19 in the Eastern Cape, South Africa |
| title_full_unstemmed | Acute kidney injury among hospitalised patients who died due to COVID-19 in the Eastern Cape, South Africa |
| title_short | Acute kidney injury among hospitalised patients who died due to COVID-19 in the Eastern Cape, South Africa |
| title_sort | acute kidney injury among hospitalised patients who died due to covid 19 in the eastern cape south africa |
| topic | aki covid-19 hospitalised comorbidity prognosis |
| url | https://safpj.co.za/index.php/safpj/article/view/5616 |
| work_keys_str_mv | AT ramprakashkaswa acutekidneyinjuryamonghospitalisedpatientswhodiedduetocovid19intheeasterncapesouthafrica |