Nightmares caused by isotretinoin in treating hidradenitis suppurativa: a case report and clinical insights
Isotretinoin, widely used for treating severe acne, has also been prescribed off-label for hidradenitis suppurativa (HS). While effective in some cases, isotretinoin is known to cause psychiatric side effects. This case report discusses a 24-year-old male with HS who developed severe nightmares aft...
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PAGEPress Publications
2024-12-01
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| Series: | Dermatology Reports |
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| Online Access: | https://www.pagepress.org/journals/dr/article/view/10171 |
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| author | Fawaz Aljehani Shumukh Alqahtani Sara Alharbi Seham Alsulami |
| author_facet | Fawaz Aljehani Shumukh Alqahtani Sara Alharbi Seham Alsulami |
| author_sort | Fawaz Aljehani |
| collection | DOAJ |
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Isotretinoin, widely used for treating severe acne, has also been prescribed off-label for hidradenitis suppurativa (HS). While effective in some cases, isotretinoin is known to cause psychiatric side effects. This case report discusses a 24-year-old male with HS who developed severe nightmares after isotretinoin dosage was increased. Initially prescribed to manage his HS symptoms, the drug led to vivid, distressing nightmares that significantly disrupted his sleep, resulting in the discontinuation of treatment. The symptoms resolved upon cessation of isotretinoin, and a probable association was confirmed using the Naranjo algorithm. The patient was later transitioned to adalimumab, a biologic therapy for HS. This case highlights the need for careful psychiatric monitoring during isotretinoin therapy and emphasizes the importance of considering alternative treatments in cases of intolerable side effects. Further research is necessary to understand better the psychiatric implications of isotretinoin, including sleep disturbances like nightmares.
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| format | Article |
| id | doaj-art-4a02a72c2d9f4483bea98ec38341d4cc |
| institution | OA Journals |
| issn | 2036-7392 2036-7406 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Dermatology Reports |
| spelling | doaj-art-4a02a72c2d9f4483bea98ec38341d4cc2025-08-20T02:21:02ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062024-12-0110.4081/dr.2024.10171Nightmares caused by isotretinoin in treating hidradenitis suppurativa: a case report and clinical insightsFawaz Aljehani0Shumukh Alqahtani1Sara Alharbi2Seham Alsulami3Department of Dermatology, King Abdulaziz Hospital, MakkahDepartment of Medicine and Surgery, College of Medicine, Umm Al-Qura University, MakkahDepartment of Dermatology, Eastern Health Cluster, DammamDepartment of Dermatology, Eastern Health Cluster, Dammam Isotretinoin, widely used for treating severe acne, has also been prescribed off-label for hidradenitis suppurativa (HS). While effective in some cases, isotretinoin is known to cause psychiatric side effects. This case report discusses a 24-year-old male with HS who developed severe nightmares after isotretinoin dosage was increased. Initially prescribed to manage his HS symptoms, the drug led to vivid, distressing nightmares that significantly disrupted his sleep, resulting in the discontinuation of treatment. The symptoms resolved upon cessation of isotretinoin, and a probable association was confirmed using the Naranjo algorithm. The patient was later transitioned to adalimumab, a biologic therapy for HS. This case highlights the need for careful psychiatric monitoring during isotretinoin therapy and emphasizes the importance of considering alternative treatments in cases of intolerable side effects. Further research is necessary to understand better the psychiatric implications of isotretinoin, including sleep disturbances like nightmares. https://www.pagepress.org/journals/dr/article/view/10171Isotretinoinhidradenitis suppurativanightmares |
| spellingShingle | Fawaz Aljehani Shumukh Alqahtani Sara Alharbi Seham Alsulami Nightmares caused by isotretinoin in treating hidradenitis suppurativa: a case report and clinical insights Dermatology Reports Isotretinoin hidradenitis suppurativa nightmares |
| title | Nightmares caused by isotretinoin in treating hidradenitis suppurativa: a case report and clinical insights |
| title_full | Nightmares caused by isotretinoin in treating hidradenitis suppurativa: a case report and clinical insights |
| title_fullStr | Nightmares caused by isotretinoin in treating hidradenitis suppurativa: a case report and clinical insights |
| title_full_unstemmed | Nightmares caused by isotretinoin in treating hidradenitis suppurativa: a case report and clinical insights |
| title_short | Nightmares caused by isotretinoin in treating hidradenitis suppurativa: a case report and clinical insights |
| title_sort | nightmares caused by isotretinoin in treating hidradenitis suppurativa a case report and clinical insights |
| topic | Isotretinoin hidradenitis suppurativa nightmares |
| url | https://www.pagepress.org/journals/dr/article/view/10171 |
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