Ethnic variation in inflammatory profile in tuberculosis.

Ethnic variation in inflammatory profile in tuberculosis.

Distinct phylogenetic lineages of Mycobacterium tuberculosis (MTB) cause disease in patients of particular genetic ancestry, and elicit different patterns of cytokine and chemokine secretion when cultured with human macrophages in vitro. Circulating and antigen-stimulated concentrations of these inf...

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Main Authors: Anna K Coussens, Robert J Wilkinson, Vladyslav Nikolayevskyy, Paul T Elkington, Yasmeen Hanifa, Kamrul Islam, Peter M Timms, Graham H Bothamley, Alleyna P Claxton, Geoffrey E Packe, Mathina Darmalingam, Robert N Davidson, Heather J Milburn, Lucy V Baker, Richard D Barker, Francis A Drobniewski, Charles A Mein, Leena Bhaw-Rosun, Rosamond A Nuamah, Christopher J Griffiths, Adrian R Martineau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003468&type=printable
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