Sophora moocroftiana seeds ethanol extract regulates NLRP3 inflammasome activation and pyroptosis via ROS/TXNIP pathway to amelioration of NAFLD in vitro and in vivo
BackgroundSophora moorcroftiana (Benth.) Baker is a perennial shrub endemic to the Tibetan Plateau. Its seeds are traditional Tibetan medicine for treating jaundice, hepatitis, purulent tonsillitis, diphtheria, and parasitosis.Aim of the studyThe aim of this research is to explore the possible proce...
Saved in:
| Main Authors: | Ruiying Yuan, Mingan Gui, Shan Huang, Yangzhen Ciren, Dongzhi Zhuoma, Guibin Yang, Wendong Zhang, Sicen Wang, Bin Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
|
| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1622178/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Thioredoxin-1 inhibits NLRP3-mediated pyroptosis by regulating TXNIP in models of Alzheimer’s disease
by: Jinjing Jia, et al.
Published: (2025-05-01) -
Seed dormancy and germination in Sophora secundiflora (Fabaceae)
by: Abdenour KHELOUFI, et al.
Published: (2024-12-01) -
Trim21 deficiency alleviates osteoporosis by inhibiting osteoclast differentiation through regulating Txnip
by: Ya-Chen Peng, et al.
Published: (2025-08-01) -
New horizon of the combined BCG vaccine with probiotic and liraglutide in augmenting beta cell survival via suppression of TXNIP/NLRP3 pyroptosis signaling in Streptozocin–Induced diabetes mellitestype-1 in rats
by: Amira Karam Khalifa, et al.
Published: (2024-10-01) -
Thioredoxin-Interacting Protein (TXNIP) in Gestational Diabetes Mellitus
by: Ioanna Kokkinopoulou, et al.
Published: (2025-05-01)