Hemolytic Uremic Syndrome Caused by Enteroviral Infection

A 4-year-old boy presented with enteroviral infection complicated with atypical hemolytic uremic syndrome (aHUS). Enterovirus RNA was detected by reverse transcription polymerase chain reaction (RT-PCR) of both blood and kidney biopsy specimens. A survey of the complement system did not reveal a spe...

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Main Authors: Ming-Dar Lee, Chin-Yuan Tzen, Chun-Chen Lin, Fu-Yuan Huang, Hsi-Che Liu, Jeng-Daw Tsai
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Pediatrics and Neonatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957212001751
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author Ming-Dar Lee
Chin-Yuan Tzen
Chun-Chen Lin
Fu-Yuan Huang
Hsi-Che Liu
Jeng-Daw Tsai
author_facet Ming-Dar Lee
Chin-Yuan Tzen
Chun-Chen Lin
Fu-Yuan Huang
Hsi-Che Liu
Jeng-Daw Tsai
author_sort Ming-Dar Lee
collection DOAJ
description A 4-year-old boy presented with enteroviral infection complicated with atypical hemolytic uremic syndrome (aHUS). Enterovirus RNA was detected by reverse transcription polymerase chain reaction (RT-PCR) of both blood and kidney biopsy specimens. A survey of the complement system did not reveal a specific complement defect. Supportive therapy with blood components transfusion, plasma therapy, and immunosuppressants was administered, however, renal function did not recover. The results of this report demonstrate that the enterovirus is the cause of aHUS.
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id doaj-art-49fbf5a8e5c84eae84885a279a29d4a5
institution Kabale University
issn 1875-9572
language English
publishDate 2013-06-01
publisher Elsevier
record_format Article
series Pediatrics and Neonatology
spelling doaj-art-49fbf5a8e5c84eae84885a279a29d4a52025-08-20T03:34:17ZengElsevierPediatrics and Neonatology1875-95722013-06-0154320721010.1016/j.pedneo.2012.10.012Hemolytic Uremic Syndrome Caused by Enteroviral InfectionMing-Dar Lee0Chin-Yuan Tzen1Chun-Chen Lin2Fu-Yuan Huang3Hsi-Che Liu4Jeng-Daw Tsai5Department of Pediatrics, Hsinchu Mackay Memorial Hospital, Hsinchu, TaiwanDepartment of Pathology and Laboratory Medicine, Cathay General Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanDepartment of Pediatrics, Mackay Memorial Hospital, Taipei, TaiwanA 4-year-old boy presented with enteroviral infection complicated with atypical hemolytic uremic syndrome (aHUS). Enterovirus RNA was detected by reverse transcription polymerase chain reaction (RT-PCR) of both blood and kidney biopsy specimens. A survey of the complement system did not reveal a specific complement defect. Supportive therapy with blood components transfusion, plasma therapy, and immunosuppressants was administered, however, renal function did not recover. The results of this report demonstrate that the enterovirus is the cause of aHUS.http://www.sciencedirect.com/science/article/pii/S1875957212001751enterovirushemolytic uremic syndromepolymerase chain reaction
spellingShingle Ming-Dar Lee
Chin-Yuan Tzen
Chun-Chen Lin
Fu-Yuan Huang
Hsi-Che Liu
Jeng-Daw Tsai
Hemolytic Uremic Syndrome Caused by Enteroviral Infection
Pediatrics and Neonatology
enterovirus
hemolytic uremic syndrome
polymerase chain reaction
title Hemolytic Uremic Syndrome Caused by Enteroviral Infection
title_full Hemolytic Uremic Syndrome Caused by Enteroviral Infection
title_fullStr Hemolytic Uremic Syndrome Caused by Enteroviral Infection
title_full_unstemmed Hemolytic Uremic Syndrome Caused by Enteroviral Infection
title_short Hemolytic Uremic Syndrome Caused by Enteroviral Infection
title_sort hemolytic uremic syndrome caused by enteroviral infection
topic enterovirus
hemolytic uremic syndrome
polymerase chain reaction
url http://www.sciencedirect.com/science/article/pii/S1875957212001751
work_keys_str_mv AT mingdarlee hemolyticuremicsyndromecausedbyenteroviralinfection
AT chinyuantzen hemolyticuremicsyndromecausedbyenteroviralinfection
AT chunchenlin hemolyticuremicsyndromecausedbyenteroviralinfection
AT fuyuanhuang hemolyticuremicsyndromecausedbyenteroviralinfection
AT hsicheliu hemolyticuremicsyndromecausedbyenteroviralinfection
AT jengdawtsai hemolyticuremicsyndromecausedbyenteroviralinfection