Methods to Predict and Lower the Risk of Prostate Cancer

Chemoprevention for prostate cancer (PCa) continues to generate interest from both physicians and the patient population. The goal of chemoprevention is to stop the malignant transformation of prostate cells into cancer. Multiple studies on different substances ranging from supplements to medical th...

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Main Authors: Barbara Ercole, Dipen J. Parekh
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2011.72
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author Barbara Ercole
Dipen J. Parekh
author_facet Barbara Ercole
Dipen J. Parekh
author_sort Barbara Ercole
collection DOAJ
description Chemoprevention for prostate cancer (PCa) continues to generate interest from both physicians and the patient population. The goal of chemoprevention is to stop the malignant transformation of prostate cells into cancer. Multiple studies on different substances ranging from supplements to medical therapy have been undertaken. Thus far, only the studies on 5α-reductase inhibitors (the Prostate Cancer Prevention Trial [PCPT] and Reduction by Dutasteride of Prostate Cancer Events [REDUCE] trial) have demonstrated a reduction in the risk of PCa, while results from the Selenium and Vitamin E Cancer Prevention Trial (SELECT) concluded no decreased risk for PCa with selenium or vitamin E.
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spelling doaj-art-49f9d612c85645e2b9588a6c3fbb2ff42025-08-20T03:34:17ZengWileyThe Scientific World Journal1537-744X2011-01-011174274810.1100/tsw.2011.72Methods to Predict and Lower the Risk of Prostate CancerBarbara Ercole0Dipen J. Parekh1Department of Urology, University of Texas Health Science Center, San Antonio, USADepartment of Urology, University of Texas Health Science Center, San Antonio, USAChemoprevention for prostate cancer (PCa) continues to generate interest from both physicians and the patient population. The goal of chemoprevention is to stop the malignant transformation of prostate cells into cancer. Multiple studies on different substances ranging from supplements to medical therapy have been undertaken. Thus far, only the studies on 5α-reductase inhibitors (the Prostate Cancer Prevention Trial [PCPT] and Reduction by Dutasteride of Prostate Cancer Events [REDUCE] trial) have demonstrated a reduction in the risk of PCa, while results from the Selenium and Vitamin E Cancer Prevention Trial (SELECT) concluded no decreased risk for PCa with selenium or vitamin E.http://dx.doi.org/10.1100/tsw.2011.72
spellingShingle Barbara Ercole
Dipen J. Parekh
Methods to Predict and Lower the Risk of Prostate Cancer
The Scientific World Journal
title Methods to Predict and Lower the Risk of Prostate Cancer
title_full Methods to Predict and Lower the Risk of Prostate Cancer
title_fullStr Methods to Predict and Lower the Risk of Prostate Cancer
title_full_unstemmed Methods to Predict and Lower the Risk of Prostate Cancer
title_short Methods to Predict and Lower the Risk of Prostate Cancer
title_sort methods to predict and lower the risk of prostate cancer
url http://dx.doi.org/10.1100/tsw.2011.72
work_keys_str_mv AT barbaraercole methodstopredictandlowertheriskofprostatecancer
AT dipenjparekh methodstopredictandlowertheriskofprostatecancer