Mapping Hsp104 interactions using cross‐linking mass spectrometry

Mapping Hsp104 interactions using cross‐linking mass spectrometry

Molecular machines from the AAA+ (ATPases Associated with diverse cellular Activity) superfamily of protein disaggregases play important roles in protein folding, disaggregation and DNA processing. Recent cryo‐EM structures of AAA+ molecular machines have uncovered nuanced changes in their conformat...

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Bibliographic Details
Main Authors: Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:FEBS Open Bio
Subjects:
Hsp104
PCSK9
protein–protein interactions
XL‐MS
Online Access:https://doi.org/10.1002/2211-5463.70007
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