Upregulation of IL-12 Signaling Genes Mediated by STAT4 Predicts a Complete Clinical Response in Patients with Squamous Cell Carcinoma of the Esophagus who Undergo Concurrent Chemoradiotherapy

Upregulation of IL-12 Signaling Genes Mediated by STAT4 Predicts a Complete Clinical Response in Patients with Squamous Cell Carcinoma of the Esophagus who Undergo Concurrent Chemoradiotherapy

Objective: This study compared immune transcriptome profiles between SCC patients achieving cCR and those with incomplete responses to CRT using the NanoString Ncounter® Pancancer Immune Profiling Panel. Materials and Methods: A retrospective cohort of 36 SCC patients treated with CRT was ana...

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Main Authors: Nattida Sapsamarn, Asada Methasate, Pariyada Tanjak, Thanawat Suwatthanarak, Onchira Acharayothin, Kullanist Thanormjit, Jirawat Swangsri, Thammawat Parakonthun, Tetsuya Taga, Vitoon Chinswangwatanakul
Format: Article
Language:English
Published: Faculty of Medicine Siriraj Hospital 2025-07-01
Series:Siriraj Medical Journal
Subjects:
Squamous cell carcinoma of the esophagus
Chemoradiotherapy
Interleukin 12
Online Access:https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/272789
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