Mesenchymal Stem Cell-Derived Exosomal miRNA-222-3p Increases Th1/Th2 Ratio and Promotes Apoptosis of Acute Myeloid Leukemia Cells

Mesenchymal Stem Cell-Derived Exosomal miRNA-222-3p Increases Th1/Th2 Ratio and Promotes Apoptosis of Acute Myeloid Leukemia Cells

Interferon regulatory factor 2 (IRF2) participates in the differentiation of immune T cells. Bone marrow mesenchymal stem cell (BM-MSC)-derived exosomes can secret mRNA, miRNAs, and proteins to regulate tumor microenvironment. The present study focused on the miRNA/IRF2 axis in regulating Th1/Th2 ra...

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Bibliographic Details
Main Authors: Yuan Yuan, Shengfen Tan, Huanhuan Wang, Junfeng Zhu, Jiajia Li, Pingping Zhang, Meng Wang, Feng Zhang
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2023/4024887
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