Autonomous nervous system responses to environmental‐level exposure to 5G's first deployed band (3.5 GHz) in healthy human volunteers

Abstract Following the global progressive deployment of 5G networks, considerable attention has focused on assessing their potential impact on human health. This study aims to investigate autonomous nervous system changes by exploring skin temperature and electrodermal activity (EDA) among 44 health...

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Main Authors: Layla Jamal, Lisa Michelant, Stéphane Delanaud, Laurent Hugueville, Paul Mazet, Philippe Lévêque, Tamara Baz, Véronique Bach, Brahim Selmaoui
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Experimental Physiology
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Online Access:https://doi.org/10.1113/EP092083
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author Layla Jamal
Lisa Michelant
Stéphane Delanaud
Laurent Hugueville
Paul Mazet
Philippe Lévêque
Tamara Baz
Véronique Bach
Brahim Selmaoui
author_facet Layla Jamal
Lisa Michelant
Stéphane Delanaud
Laurent Hugueville
Paul Mazet
Philippe Lévêque
Tamara Baz
Véronique Bach
Brahim Selmaoui
author_sort Layla Jamal
collection DOAJ
description Abstract Following the global progressive deployment of 5G networks, considerable attention has focused on assessing their potential impact on human health. This study aims to investigate autonomous nervous system changes by exploring skin temperature and electrodermal activity (EDA) among 44 healthy young individuals of both sexes during and after exposure to 3.5 GHz antenna‐emitted signals, with an electrical field intensity ranging from 1 to 2 V/m. The study employed a randomized, cross‐over design with triple‐blinding, encompassing both ‘real’ and ‘sham’ exposure sessions, separated by a maximum interval of 1 week. Each session comprised baseline, exposure and postexposure phases, resulting in the acquisition of seven runs. Each run initiated with a 150 s segment of EDA recordings stimulated by 10 repeated beeps. Subsequently, the collected data underwent continuous decomposition analysis, generating specific indicators assessed alongside standard metrics such as trough‐to‐peak measurements, global skin conductance and maximum positive peak deflection. Additionally, non‐invasive, real‐time skin temperature measurements were conducted to evaluate specific anatomical points (hand, head and neck). The study suggests that exposure to 3.5 GHz signals may potentially affect head and neck temperature, indicating a slight increase in this parameter. Furthermore, there was a minimal modulation of certain electrodermal metrics after the exposure, suggesting a potentially faster physiological response to auditory stimulation. However, while the results are significant, they remain within the normal physiological range and could be a consequence of an uncontrolled variable. Given the preliminary nature of this pilot study, further research is needed to confirm the effects of 5G exposure.
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spelling doaj-art-49dfa23f595b4b9fb45deecfb3e4ae012025-08-20T02:07:13ZengWileyExperimental Physiology0958-06701469-445X2024-12-01109122122213310.1113/EP092083Autonomous nervous system responses to environmental‐level exposure to 5G's first deployed band (3.5 GHz) in healthy human volunteersLayla Jamal0Lisa Michelant1Stéphane Delanaud2Laurent Hugueville3Paul Mazet4Philippe Lévêque5Tamara Baz6Véronique Bach7Brahim Selmaoui8Department of Experimental Toxicology and Modeling (TEAM) Institut National de l'Environnement Industriel et des Risques (INERIS) Verneuil‐en‐Halatte FranceDepartment of Experimental Toxicology and Modeling (TEAM) Institut National de l'Environnement Industriel et des Risques (INERIS) Verneuil‐en‐Halatte FrancePériTox laboratory (UMR_I 01), UPJV/INERIS University of Picardy Jules Verne Amiens FranceParis Brain Institute (ICM) Center for NeuroImaging Research (CENIR) Sorbonne University, INSERM U1127, CNRS UMR7225, Pitié‐Salpêtrière Hospital Paris FranceDepartment of Electromagnetic Compatibility Technical Center for Mechanical Industries (CETIM) Senlis FranceRF and Printed ELectronics for Telecom and Energy team University of Limoges, CNRS, XLIM, UMR 7252 Limoges FranceDepartment of Experimental Toxicology and Modeling (TEAM) Institut National de l'Environnement Industriel et des Risques (INERIS) Verneuil‐en‐Halatte FrancePériTox laboratory (UMR_I 01), UPJV/INERIS University of Picardy Jules Verne Amiens FranceDepartment of Experimental Toxicology and Modeling (TEAM) Institut National de l'Environnement Industriel et des Risques (INERIS) Verneuil‐en‐Halatte FranceAbstract Following the global progressive deployment of 5G networks, considerable attention has focused on assessing their potential impact on human health. This study aims to investigate autonomous nervous system changes by exploring skin temperature and electrodermal activity (EDA) among 44 healthy young individuals of both sexes during and after exposure to 3.5 GHz antenna‐emitted signals, with an electrical field intensity ranging from 1 to 2 V/m. The study employed a randomized, cross‐over design with triple‐blinding, encompassing both ‘real’ and ‘sham’ exposure sessions, separated by a maximum interval of 1 week. Each session comprised baseline, exposure and postexposure phases, resulting in the acquisition of seven runs. Each run initiated with a 150 s segment of EDA recordings stimulated by 10 repeated beeps. Subsequently, the collected data underwent continuous decomposition analysis, generating specific indicators assessed alongside standard metrics such as trough‐to‐peak measurements, global skin conductance and maximum positive peak deflection. Additionally, non‐invasive, real‐time skin temperature measurements were conducted to evaluate specific anatomical points (hand, head and neck). The study suggests that exposure to 3.5 GHz signals may potentially affect head and neck temperature, indicating a slight increase in this parameter. Furthermore, there was a minimal modulation of certain electrodermal metrics after the exposure, suggesting a potentially faster physiological response to auditory stimulation. However, while the results are significant, they remain within the normal physiological range and could be a consequence of an uncontrolled variable. Given the preliminary nature of this pilot study, further research is needed to confirm the effects of 5G exposure.https://doi.org/10.1113/EP092083autonomous nervous systemevent‐related responsesfifth generationradio frequenciesskin conductancethermal effects
spellingShingle Layla Jamal
Lisa Michelant
Stéphane Delanaud
Laurent Hugueville
Paul Mazet
Philippe Lévêque
Tamara Baz
Véronique Bach
Brahim Selmaoui
Autonomous nervous system responses to environmental‐level exposure to 5G's first deployed band (3.5 GHz) in healthy human volunteers
Experimental Physiology
autonomous nervous system
event‐related responses
fifth generation
radio frequencies
skin conductance
thermal effects
title Autonomous nervous system responses to environmental‐level exposure to 5G's first deployed band (3.5 GHz) in healthy human volunteers
title_full Autonomous nervous system responses to environmental‐level exposure to 5G's first deployed band (3.5 GHz) in healthy human volunteers
title_fullStr Autonomous nervous system responses to environmental‐level exposure to 5G's first deployed band (3.5 GHz) in healthy human volunteers
title_full_unstemmed Autonomous nervous system responses to environmental‐level exposure to 5G's first deployed band (3.5 GHz) in healthy human volunteers
title_short Autonomous nervous system responses to environmental‐level exposure to 5G's first deployed band (3.5 GHz) in healthy human volunteers
title_sort autonomous nervous system responses to environmental level exposure to 5g s first deployed band 3 5 ghz in healthy human volunteers
topic autonomous nervous system
event‐related responses
fifth generation
radio frequencies
skin conductance
thermal effects
url https://doi.org/10.1113/EP092083
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