Metals and Breast Cancer: Risk Factors or Healing Agents?

Metals and metal compounds are part of our environment. Several metals are essential for physiological functions (e.g., zinc or magnesium); while the beneficial effects of others are uncertain (e.g., manganese), some metals are proven to be toxic (e.g., mercury, lead). Additionally there are organic...

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Main Authors: Ana-Maria Florea, Dietrich Büsselberg
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2011/159619
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author Ana-Maria Florea
Dietrich Büsselberg
author_facet Ana-Maria Florea
Dietrich Büsselberg
author_sort Ana-Maria Florea
collection DOAJ
description Metals and metal compounds are part of our environment. Several metals are essential for physiological functions (e.g., zinc or magnesium); while the beneficial effects of others are uncertain (e.g., manganese), some metals are proven to be toxic (e.g., mercury, lead). Additionally there are organic metal compounds; some of them are extremely toxic (e.g., trimethyltin, methylmercury), but there is very little knowledge available how they are handled by organisms. Scientific evidence indicates that long-term exposure to (some) metallic compounds induces different forms of cancer, including breast cancer. On the other side, several metal compounds have clinical use in treating life-threatening diseases such as cancer. In this paper we discuss the recent literature that shows a correlation between metal exposure and breast cancer.
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series Journal of Toxicology
spelling doaj-art-49df33d515cd48f8a220c5488842d20e2025-02-03T05:51:41ZengWileyJournal of Toxicology1687-81911687-82052011-01-01201110.1155/2011/159619159619Metals and Breast Cancer: Risk Factors or Healing Agents?Ana-Maria Florea0Dietrich Büsselberg1Department of Neuropathology, Heinrich-Heine University, 40225 Düsseldorf, GermanyWeill Cornell Medical College in Qatar, Qatar Foundation, Education City, P.O. Box 24144, Doha, QatarMetals and metal compounds are part of our environment. Several metals are essential for physiological functions (e.g., zinc or magnesium); while the beneficial effects of others are uncertain (e.g., manganese), some metals are proven to be toxic (e.g., mercury, lead). Additionally there are organic metal compounds; some of them are extremely toxic (e.g., trimethyltin, methylmercury), but there is very little knowledge available how they are handled by organisms. Scientific evidence indicates that long-term exposure to (some) metallic compounds induces different forms of cancer, including breast cancer. On the other side, several metal compounds have clinical use in treating life-threatening diseases such as cancer. In this paper we discuss the recent literature that shows a correlation between metal exposure and breast cancer.http://dx.doi.org/10.1155/2011/159619
spellingShingle Ana-Maria Florea
Dietrich Büsselberg
Metals and Breast Cancer: Risk Factors or Healing Agents?
Journal of Toxicology
title Metals and Breast Cancer: Risk Factors or Healing Agents?
title_full Metals and Breast Cancer: Risk Factors or Healing Agents?
title_fullStr Metals and Breast Cancer: Risk Factors or Healing Agents?
title_full_unstemmed Metals and Breast Cancer: Risk Factors or Healing Agents?
title_short Metals and Breast Cancer: Risk Factors or Healing Agents?
title_sort metals and breast cancer risk factors or healing agents
url http://dx.doi.org/10.1155/2011/159619
work_keys_str_mv AT anamariaflorea metalsandbreastcancerriskfactorsorhealingagents
AT dietrichbusselberg metalsandbreastcancerriskfactorsorhealingagents