The CENPN/STAT3/USP37 signaling axis promotes invasion, migration and metastasis in nasopharyngeal carcinoma

The CENPN/STAT3/USP37 signaling axis promotes invasion, migration and metastasis in nasopharyngeal carcinoma

BackgroundNasopharyngeal carcinoma (NPC) metastasis is the main cause of poor treatment outcomes and death in nasopharyngeal carcinoma patients. Previously, we reported that centromere protein N (CENPN) is closely related to the pathogenesis, radiotherapy resistance and chemotherapy resistance of na...

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Bibliographic Details
Main Authors: Yu-Fei Wang, You Zou, Yue-Long Qiao, Li-Zhi Wu, Shan Xu, Rui Yang, Wo-Er Jiao, Shi-Ming Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
transcriptional regulation
nasopharyngeal carcinoma
metastasis
CENPN
STAT3
USP37
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1536574/full
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