Odontogenic brain abscess caused by Porphyromonas gingivalis and Streptococcus constellatus: a case report and review article
Background Odontogenic brain abscess is a rare, but potentially fatal, central nervous system infection, with insidious onset and unclear etiology.Methods This case reports a 70-year-old male patient who developed an odontogenic brain abscess secondary to periodontal infection and underwent neurolog...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Journal of Oral Microbiology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/20002297.2025.2485197 |
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| author | Siyu Sun Rui He Shan Chen Jing Ren Xinrong Ma Junying Yang |
| author_facet | Siyu Sun Rui He Shan Chen Jing Ren Xinrong Ma Junying Yang |
| author_sort | Siyu Sun |
| collection | DOAJ |
| description | Background Odontogenic brain abscess is a rare, but potentially fatal, central nervous system infection, with insidious onset and unclear etiology.Methods This case reports a 70-year-old male patient who developed an odontogenic brain abscess secondary to periodontal infection and underwent neurological surgery. Extract pus during surgery for the metagenomic next-generation sequencing (mNGS).Results The mNGS of pus samples obtained from brain abscess aspiration identified the periodontal pathogens Porphyromonas gingivalis and Streptococcus constellatus. Consequently, he was referred to the department of stomatology for further examination and treatment.Conclusions Our study found that major periodontal pathogens including P. gingivalis and S. constellatus were essential in the development of odontogenic brain abscesses; thus, timely intervention and preventive measures are important for treatment. |
| format | Article |
| id | doaj-art-49be0acf98c549e687ec2d7fc380b587 |
| institution | OA Journals |
| issn | 2000-2297 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Oral Microbiology |
| spelling | doaj-art-49be0acf98c549e687ec2d7fc380b5872025-08-20T02:12:19ZengTaylor & Francis GroupJournal of Oral Microbiology2000-22972025-12-0117110.1080/20002297.2025.2485197Odontogenic brain abscess caused by Porphyromonas gingivalis and Streptococcus constellatus: a case report and review articleSiyu Sun0Rui He1Shan Chen2Jing Ren3Xinrong Ma4Junying Yang5Department of Stomatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Stomatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Stomatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Stomatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Stomatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Stomatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, ChinaBackground Odontogenic brain abscess is a rare, but potentially fatal, central nervous system infection, with insidious onset and unclear etiology.Methods This case reports a 70-year-old male patient who developed an odontogenic brain abscess secondary to periodontal infection and underwent neurological surgery. Extract pus during surgery for the metagenomic next-generation sequencing (mNGS).Results The mNGS of pus samples obtained from brain abscess aspiration identified the periodontal pathogens Porphyromonas gingivalis and Streptococcus constellatus. Consequently, he was referred to the department of stomatology for further examination and treatment.Conclusions Our study found that major periodontal pathogens including P. gingivalis and S. constellatus were essential in the development of odontogenic brain abscesses; thus, timely intervention and preventive measures are important for treatment.https://www.tandfonline.com/doi/10.1080/20002297.2025.2485197Brain abscessperiodontitisPorphyromonas gingivalisStreptococcus constellatusmNGS |
| spellingShingle | Siyu Sun Rui He Shan Chen Jing Ren Xinrong Ma Junying Yang Odontogenic brain abscess caused by Porphyromonas gingivalis and Streptococcus constellatus: a case report and review article Journal of Oral Microbiology Brain abscess periodontitis Porphyromonas gingivalis Streptococcus constellatus mNGS |
| title | Odontogenic brain abscess caused by Porphyromonas gingivalis and Streptococcus constellatus: a case report and review article |
| title_full | Odontogenic brain abscess caused by Porphyromonas gingivalis and Streptococcus constellatus: a case report and review article |
| title_fullStr | Odontogenic brain abscess caused by Porphyromonas gingivalis and Streptococcus constellatus: a case report and review article |
| title_full_unstemmed | Odontogenic brain abscess caused by Porphyromonas gingivalis and Streptococcus constellatus: a case report and review article |
| title_short | Odontogenic brain abscess caused by Porphyromonas gingivalis and Streptococcus constellatus: a case report and review article |
| title_sort | odontogenic brain abscess caused by porphyromonas gingivalis and streptococcus constellatus a case report and review article |
| topic | Brain abscess periodontitis Porphyromonas gingivalis Streptococcus constellatus mNGS |
| url | https://www.tandfonline.com/doi/10.1080/20002297.2025.2485197 |
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