Spatial and signal features of white matter integrity and associations with clinical factors: A CARDIA brain MRI study

Spatial and signal features of white matter integrity and associations with clinical factors: A CARDIA brain MRI study

White matter hyperintensities (WMH) may be indicative of age-related cerebrovascular diseases and contribute to cognitive and functional decline. Normal appearing WM (NAWM) adjacent to WMH, termed “penumbra,” is known to be vulnerable to future WMH pathology. WM integrity can be evaluated using mult...

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Bibliographic Details
Main Authors: Faezeh Vedaei, Dhivya Srinivasan, Drew Parker, Guray Erus, Sudipto Dolui, Farzaneh A. Sorond, David R. Jacobs, Jr, Lenore J. Launer, Daniel T. Lackland, Christos Davatzikos, R.Nick Bryan, Ilya M. Nasrallah
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:NeuroImage: Clinical
Subjects:
White matter hyperintensity
Fluid attenuated inversion recovery
Diffusion tensor imaging
Cerebral blood flow
Hypertension
Cognitive function
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158225000385
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