Neoadjuvant immunochemotherapy for locally advanced esophageal squamous cell carcinoma in real-world practice: an analysis of the clinical outcomes and long-term survival, and the feasibility of using major pathological response as a surrogate endpoint

Neoadjuvant immunochemotherapy for locally advanced esophageal squamous cell carcinoma in real-world practice: an analysis of the clinical outcomes and long-term survival, and the feasibility of using major pathological response as a surrogate endpoint

Abstract Background Neoadjuvant immunochemotherapy is expected to become the standard treatment mode for locally advanced esophageal squamous cell carcinoma (ESCC). This study aims to analyze the clinical outcomes and long-term survival of neoadjuvant immunochemotherapy for locally advanced ESCC, an...

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Bibliographic Details
Main Authors: Jiacong Liu, Ziheng Wu, Shihong Zhou, Wang Lv, Yiqing Wang, Pinghui Xia, Linhai Zhu, Jian Hu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:European Journal of Medical Research
Subjects:
Esophageal squamous cell carcinoma (ESCC)
Locally advanced
Neoadjuvant immunochemotherapy
Survival
Surrogate endpoint
Online Access:https://doi.org/10.1186/s40001-025-02599-z
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