Mixed Medullary-Follicular Carcinoma of the Thyroid
Introduction. Mixed medullary-follicular thyroid carcinoma is an uncommon tumor that consists of both follicular and parafollicular cells. Case. We report a 43-year-old woman with a palpable mass in the right side of the neck. Fine needle aspiration suggested a diagnosis of high grade anaplastic car...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2013/571692 |
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| author | Maasumeh Tohidi Gholamreza Pourbehi Mohammad Bahmanyar Seyed Sajjad Eghbali Mohammadreza Kalantar Hormozi Iraj Nabipour |
| author_facet | Maasumeh Tohidi Gholamreza Pourbehi Mohammad Bahmanyar Seyed Sajjad Eghbali Mohammadreza Kalantar Hormozi Iraj Nabipour |
| author_sort | Maasumeh Tohidi |
| collection | DOAJ |
| description | Introduction. Mixed medullary-follicular thyroid carcinoma is an uncommon tumor that consists of both follicular and parafollicular cells. Case. We report a 43-year-old woman with a palpable mass in the right side of the neck. Fine needle aspiration suggested a diagnosis of high grade anaplastic carcinoma that has been associated with papillary features. Total thyroidectomy was done in which histopathological examination showed diagnosis of medullary carcinoma. Immunohistochemical staining was positive for chromogranin, calcitonin, and thyroglobulin in tumoral cells. Conclusion. Mixed medullary-follicular thyroid carcinoma is a rare tumor. Diagnosis of these tumors with fine needle aspiration is very difficult and may lead to misdiagnosis. It is necessary to correlate the cytological finding with serum calcitonin and thyroglobulin. Also immunostaining for calcitonin and thyroglobulin confirms diagnosis. |
| format | Article |
| id | doaj-art-499565f268a6423888659f8a2d7b9897 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-499565f268a6423888659f8a2d7b98972025-02-03T05:50:10ZengWileyCase Reports in Endocrinology2090-65012090-651X2013-01-01201310.1155/2013/571692571692Mixed Medullary-Follicular Carcinoma of the ThyroidMaasumeh Tohidi0Gholamreza Pourbehi1Mohammad Bahmanyar2Seyed Sajjad Eghbali3Mohammadreza Kalantar Hormozi4Iraj Nabipour5The Persian Gulf Marine Medicine Biotechnology Research Center, Department of Endocrinology, Bushehr University of Medical Sciences, Bushehr, IranThe Persian Gulf Marine Medicine Biotechnology Research Center, Bushehr University of Medical Sciences, Bushehr, IranThe Persian Gulf Marine Medicine Biotechnology Research Center, Bushehr University of Medical Sciences, Bushehr, IranThe Persian Gulf Marine Medicine Biotechnology Research Center, Department of Pathology, Bushehr University of Medical Sciences, Bushehr, IranThe Persian Gulf Marine Medicine Biotechnology Research Center, Department of Endocrinology, Bushehr University of Medical Sciences, Bushehr, IranThe Persian Gulf Marine Medicine Biotechnology Research Center, Department of Endocrinology, Bushehr University of Medical Sciences, Bushehr, IranIntroduction. Mixed medullary-follicular thyroid carcinoma is an uncommon tumor that consists of both follicular and parafollicular cells. Case. We report a 43-year-old woman with a palpable mass in the right side of the neck. Fine needle aspiration suggested a diagnosis of high grade anaplastic carcinoma that has been associated with papillary features. Total thyroidectomy was done in which histopathological examination showed diagnosis of medullary carcinoma. Immunohistochemical staining was positive for chromogranin, calcitonin, and thyroglobulin in tumoral cells. Conclusion. Mixed medullary-follicular thyroid carcinoma is a rare tumor. Diagnosis of these tumors with fine needle aspiration is very difficult and may lead to misdiagnosis. It is necessary to correlate the cytological finding with serum calcitonin and thyroglobulin. Also immunostaining for calcitonin and thyroglobulin confirms diagnosis.http://dx.doi.org/10.1155/2013/571692 |
| spellingShingle | Maasumeh Tohidi Gholamreza Pourbehi Mohammad Bahmanyar Seyed Sajjad Eghbali Mohammadreza Kalantar Hormozi Iraj Nabipour Mixed Medullary-Follicular Carcinoma of the Thyroid Case Reports in Endocrinology |
| title | Mixed Medullary-Follicular Carcinoma of the Thyroid |
| title_full | Mixed Medullary-Follicular Carcinoma of the Thyroid |
| title_fullStr | Mixed Medullary-Follicular Carcinoma of the Thyroid |
| title_full_unstemmed | Mixed Medullary-Follicular Carcinoma of the Thyroid |
| title_short | Mixed Medullary-Follicular Carcinoma of the Thyroid |
| title_sort | mixed medullary follicular carcinoma of the thyroid |
| url | http://dx.doi.org/10.1155/2013/571692 |
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