Impact of traditional Chinese medicine on the prognosis of COVID-19 in cancer patients: a questionnaire-based survey

Introduction: The coronavirus disease 2019 (COVID-19) pandemic, exacerbated by the emergence of new variants such as Omicron, has posed significant challenges to healthcare systems worldwide. This study aimed to explore the potential effectiveness of long-term traditional Chinese medicine (TCM) use...

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Main Authors: Man Yao, Shuhui Tang, Xiaowan Xu, Guo Chen, Min Liu, Yannan Xu, Shuang Xiang, Xuan Zhang, Xiaofeng Zhai, Hetong Zhao
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2025-06-01
Series:Journal of Infection in Developing Countries
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Online Access:https://www.jidc.org/index.php/journal/article/view/20064
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author Man Yao
Shuhui Tang
Xiaowan Xu
Guo Chen
Min Liu
Yannan Xu
Shuang Xiang
Xuan Zhang
Xiaofeng Zhai
Hetong Zhao
author_facet Man Yao
Shuhui Tang
Xiaowan Xu
Guo Chen
Min Liu
Yannan Xu
Shuang Xiang
Xuan Zhang
Xiaofeng Zhai
Hetong Zhao
author_sort Man Yao
collection DOAJ
description Introduction: The coronavirus disease 2019 (COVID-19) pandemic, exacerbated by the emergence of new variants such as Omicron, has posed significant challenges to healthcare systems worldwide. This study aimed to explore the potential effectiveness of long-term traditional Chinese medicine (TCM) use on COVID-19 infection and post-infection symptoms in cancer patients. Methodology: An anonymous online questionnaire was used to interview cancer patients who had used TCM (TCM group) and those who had never used TCM (non-TCM group) from March 31 to April 30,2023. A self-reported questionnaire was developed to investigate and analyze the patients’ demography, underlying cancer types, treatment (TCM or non-TCM), clinical symptoms, and post-acute COVID-19 related symptoms. Results: A total of 996 cancer patients participated (607 TCM, 389 non-TCM). The non-TCM group had a higher infection rate (84.1% vs. 75.8%, p = 0.002). The TCM group reported significantly lower levels of post-COVID-19 symptoms at 3 months post-infection. Specifically, 98.0% of the TCM group reported no fatigue (91.7% in the non-TCM group, p < 0.001), and 98.7% reported no sleep difficulties (88.7% in the non-TCM group, p < 0.001). The median infection duration was 7 days in both groups, median body temperature was 38.2 °C in TCM and 38.3 °C in non-TCM group, and the fever duration was 2 days in both groups. Conclusions: There was a potential association between long-term TCM use and improved COVID-19 outcomes among cancer patients. Further research is essential to validate these findings and decipher the underlying mechanisms.
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publisher The Journal of Infection in Developing Countries
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spelling doaj-art-4992d37b3bb143c7b38596708c3afb872025-08-20T03:29:18ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802025-06-01190610.3855/jidc.20064Impact of traditional Chinese medicine on the prognosis of COVID-19 in cancer patients: a questionnaire-based surveyMan Yao0Shuhui Tang1Xiaowan Xu2Guo Chen3Min Liu4Yannan Xu5Shuang Xiang6Xuan Zhang7Xiaofeng Zhai8Hetong Zhao9Department of Integrative Oncology, The First Affiliated Hospital of Naval Medical University, Shanghai, ChinaDepartment of Oncology, The First Affiliated Hospital of Naval Medical University, Shanghai, ChinaDepartment of Integrative Oncology, The First Affiliated Hospital of Naval Medical University, Shanghai, ChinaDepartment of Integrative Oncology, The First Affiliated Hospital of Naval Medical University, Shanghai, ChinaDepartment of Integrative Oncology, The First Affiliated Hospital of Naval Medical University, Shanghai, ChinaSchool of Traditional Chinese Medicine, Naval Medical University, Shanghai, ChinaSchool of Traditional Chinese Medicine, Naval Medical University, Shanghai, ChinaDepartment of Traditional Chinese Medicine, Navy NO.905 Hospital, Naval Medical University, Shanghai, ChinaDepartment of Integrative Oncology, The First Affiliated Hospital of Naval Medical University, Shanghai, ChinaDepartment of Integrative Oncology, The First Affiliated Hospital of Naval Medical University, Shanghai, China Introduction: The coronavirus disease 2019 (COVID-19) pandemic, exacerbated by the emergence of new variants such as Omicron, has posed significant challenges to healthcare systems worldwide. This study aimed to explore the potential effectiveness of long-term traditional Chinese medicine (TCM) use on COVID-19 infection and post-infection symptoms in cancer patients. Methodology: An anonymous online questionnaire was used to interview cancer patients who had used TCM (TCM group) and those who had never used TCM (non-TCM group) from March 31 to April 30,2023. A self-reported questionnaire was developed to investigate and analyze the patients’ demography, underlying cancer types, treatment (TCM or non-TCM), clinical symptoms, and post-acute COVID-19 related symptoms. Results: A total of 996 cancer patients participated (607 TCM, 389 non-TCM). The non-TCM group had a higher infection rate (84.1% vs. 75.8%, p = 0.002). The TCM group reported significantly lower levels of post-COVID-19 symptoms at 3 months post-infection. Specifically, 98.0% of the TCM group reported no fatigue (91.7% in the non-TCM group, p < 0.001), and 98.7% reported no sleep difficulties (88.7% in the non-TCM group, p < 0.001). The median infection duration was 7 days in both groups, median body temperature was 38.2 °C in TCM and 38.3 °C in non-TCM group, and the fever duration was 2 days in both groups. Conclusions: There was a potential association between long-term TCM use and improved COVID-19 outcomes among cancer patients. Further research is essential to validate these findings and decipher the underlying mechanisms. https://www.jidc.org/index.php/journal/article/view/20064COVID-19OmicronTCMnon-TCMcancer patients
spellingShingle Man Yao
Shuhui Tang
Xiaowan Xu
Guo Chen
Min Liu
Yannan Xu
Shuang Xiang
Xuan Zhang
Xiaofeng Zhai
Hetong Zhao
Impact of traditional Chinese medicine on the prognosis of COVID-19 in cancer patients: a questionnaire-based survey
Journal of Infection in Developing Countries
COVID-19
Omicron
TCM
non-TCM
cancer patients
title Impact of traditional Chinese medicine on the prognosis of COVID-19 in cancer patients: a questionnaire-based survey
title_full Impact of traditional Chinese medicine on the prognosis of COVID-19 in cancer patients: a questionnaire-based survey
title_fullStr Impact of traditional Chinese medicine on the prognosis of COVID-19 in cancer patients: a questionnaire-based survey
title_full_unstemmed Impact of traditional Chinese medicine on the prognosis of COVID-19 in cancer patients: a questionnaire-based survey
title_short Impact of traditional Chinese medicine on the prognosis of COVID-19 in cancer patients: a questionnaire-based survey
title_sort impact of traditional chinese medicine on the prognosis of covid 19 in cancer patients a questionnaire based survey
topic COVID-19
Omicron
TCM
non-TCM
cancer patients
url https://www.jidc.org/index.php/journal/article/view/20064
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