Skin whitening potential of extracts from discarded cabbage outer leaves
Abstract The outer leaves (OL) of Brassica oleracea var. capitata (cabbage) are often discarded as agricultural waste despite their potential health benefits. This study evaluated the skin-whitening, antioxidant, and anti-inflammatory activities of cabbage OL extract (OLE) and compared them with tho...
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Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-03568-6 |
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| author | Hamin Lee Kichan Kim Kyungtae Park Bo-Kook Jang Ju-Sung Cho |
| author_facet | Hamin Lee Kichan Kim Kyungtae Park Bo-Kook Jang Ju-Sung Cho |
| author_sort | Hamin Lee |
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| description | Abstract The outer leaves (OL) of Brassica oleracea var. capitata (cabbage) are often discarded as agricultural waste despite their potential health benefits. This study evaluated the skin-whitening, antioxidant, and anti-inflammatory activities of cabbage OL extract (OLE) and compared them with those of cabbage head extract (CHE). OLE exhibited significantly higher levels of total polyphenols, flavonoids, and glucosinolates than did CHE, leading to excellent radical scavenging activities. Additionally, OLE demonstrated strong anti-inflammatory activity by reducing nitric oxide production in RAW 264.7 macrophages. Notably, tyrosinase inhibition activity of OLE reached 100.4% with respect to that of ascorbic acid, a well-known skin-whitening agent. Vitamin C and trace amounts of sulforaphane in OLE, which were absent in CHE, probably contributed to these effects. These findings suggest that cabbage OL, an agricultural byproduct, holds significant promise as a functional ingredient for health products and cosmetics, highlighting its potential for waste valorization. |
| format | Article |
| id | doaj-art-499025c5739f44fcbff13d779ac40e75 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-499025c5739f44fcbff13d779ac40e752025-08-20T03:46:00ZengNature PortfolioScientific Reports2045-23222025-07-011511910.1038/s41598-025-03568-6Skin whitening potential of extracts from discarded cabbage outer leavesHamin Lee0Kichan Kim1Kyungtae Park2Bo-Kook Jang3Ju-Sung Cho4Division of Animal, Horticultural and Food Sciences, Chungbuk National UniversityDivision of Animal, Horticultural and Food Sciences, Chungbuk National UniversityDivision of Animal, Horticultural and Food Sciences, Chungbuk National UniversityDepartment of Horticulture, Sunchon National UniversityDivision of Animal, Horticultural and Food Sciences, Chungbuk National UniversityAbstract The outer leaves (OL) of Brassica oleracea var. capitata (cabbage) are often discarded as agricultural waste despite their potential health benefits. This study evaluated the skin-whitening, antioxidant, and anti-inflammatory activities of cabbage OL extract (OLE) and compared them with those of cabbage head extract (CHE). OLE exhibited significantly higher levels of total polyphenols, flavonoids, and glucosinolates than did CHE, leading to excellent radical scavenging activities. Additionally, OLE demonstrated strong anti-inflammatory activity by reducing nitric oxide production in RAW 264.7 macrophages. Notably, tyrosinase inhibition activity of OLE reached 100.4% with respect to that of ascorbic acid, a well-known skin-whitening agent. Vitamin C and trace amounts of sulforaphane in OLE, which were absent in CHE, probably contributed to these effects. These findings suggest that cabbage OL, an agricultural byproduct, holds significant promise as a functional ingredient for health products and cosmetics, highlighting its potential for waste valorization.https://doi.org/10.1038/s41598-025-03568-6Agricultural wasteErucinFunctional cosmetic materialsGlucosinolateSulforaphaneTyrosinase Inhibition activity |
| spellingShingle | Hamin Lee Kichan Kim Kyungtae Park Bo-Kook Jang Ju-Sung Cho Skin whitening potential of extracts from discarded cabbage outer leaves Scientific Reports Agricultural waste Erucin Functional cosmetic materials Glucosinolate Sulforaphane Tyrosinase Inhibition activity |
| title | Skin whitening potential of extracts from discarded cabbage outer leaves |
| title_full | Skin whitening potential of extracts from discarded cabbage outer leaves |
| title_fullStr | Skin whitening potential of extracts from discarded cabbage outer leaves |
| title_full_unstemmed | Skin whitening potential of extracts from discarded cabbage outer leaves |
| title_short | Skin whitening potential of extracts from discarded cabbage outer leaves |
| title_sort | skin whitening potential of extracts from discarded cabbage outer leaves |
| topic | Agricultural waste Erucin Functional cosmetic materials Glucosinolate Sulforaphane Tyrosinase Inhibition activity |
| url | https://doi.org/10.1038/s41598-025-03568-6 |
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