EXPERIENCE OF APPLICATION OF SAZAR IN POLYTHERAPY AT SICK OF THE EPILEPSY WITH PARTIAL AND GENERALIZED TONIC-CLONIC CONVULSIVE ATTACKS

Studied efficiency of application Sazar (lamotrigin, Alcaloid, Macedonia) in polytherapy at sick of an epilepsy with partial and generalized tonic-clonic convulsive attacks, and also dynamics of disturbing frustration with application of a scale of alarm of Hamilton (HARS) and activity of vegetative...

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Main Authors: A. S. Shershever, E. V. Sorokova, A. Y. Lazarev
Format: Article
Language:Russian
Published: IRBIS LLC 2016-09-01
Series:Эпилепсия и пароксизмальные состояния
Subjects:
Online Access:https://www.epilepsia.su/jour/article/view/271
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author A. S. Shershever
E. V. Sorokova
A. Y. Lazarev
author_facet A. S. Shershever
E. V. Sorokova
A. Y. Lazarev
author_sort A. S. Shershever
collection DOAJ
description Studied efficiency of application Sazar (lamotrigin, Alcaloid, Macedonia) in polytherapy at sick of an epilepsy with partial and generalized tonic-clonic convulsive attacks, and also dynamics of disturbing frustration with application of a scale of alarm of Hamilton (HARS) and activity of vegetative nervous system on an index of Kerdo. 214 patients at the age from 15 to 71 years are treated. Used doses of a preparation from 150 mg to 450 mg per day. Research has shown that preparation action comparably on anti-spasm to effect with action lamotrigin. In groups of patients with cryptogenic and a symptomatic epilepsy reduction of quantity of attacks more than on 50% through 12 months after Sazar addition, and in group with an idiopathic epilepsy reduction of attacks more than on 90% per month were noted. The influence spectrum on symptoms of alarm and an index of Kerdo has appeared uniform throughout all period of supervision from 8 to 22 months.
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institution Kabale University
issn 2077-8333
2311-4088
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series Эпилепсия и пароксизмальные состояния
spelling doaj-art-497b2f833c3c458793cbb738644d64612025-08-20T03:39:32ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882016-09-01433440270EXPERIENCE OF APPLICATION OF SAZAR IN POLYTHERAPY AT SICK OF THE EPILEPSY WITH PARTIAL AND GENERALIZED TONIC-CLONIC CONVULSIVE ATTACKSA. S. Shershever0E. V. Sorokova1A. Y. Lazarev2SPHI «Sverdlovsk Regional Oncology Center», YekaterinburgMAI «City clinical hospital № 40», YekaterinburgSPHI «Sverdlovsk Regional Oncology Center», YekaterinburgStudied efficiency of application Sazar (lamotrigin, Alcaloid, Macedonia) in polytherapy at sick of an epilepsy with partial and generalized tonic-clonic convulsive attacks, and also dynamics of disturbing frustration with application of a scale of alarm of Hamilton (HARS) and activity of vegetative nervous system on an index of Kerdo. 214 patients at the age from 15 to 71 years are treated. Used doses of a preparation from 150 mg to 450 mg per day. Research has shown that preparation action comparably on anti-spasm to effect with action lamotrigin. In groups of patients with cryptogenic and a symptomatic epilepsy reduction of quantity of attacks more than on 50% through 12 months after Sazar addition, and in group with an idiopathic epilepsy reduction of attacks more than on 90% per month were noted. The influence spectrum on symptoms of alarm and an index of Kerdo has appeared uniform throughout all period of supervision from 8 to 22 months.https://www.epilepsia.su/jour/article/view/271sazarepilepsysymptomaticcryptogeneidiopathichamilton anxiety rating scale (hars)an index of kerdo
spellingShingle A. S. Shershever
E. V. Sorokova
A. Y. Lazarev
EXPERIENCE OF APPLICATION OF SAZAR IN POLYTHERAPY AT SICK OF THE EPILEPSY WITH PARTIAL AND GENERALIZED TONIC-CLONIC CONVULSIVE ATTACKS
Эпилепсия и пароксизмальные состояния
sazar
epilepsy
symptomatic
cryptogene
idiopathic
hamilton anxiety rating scale (hars)
an index of kerdo
title EXPERIENCE OF APPLICATION OF SAZAR IN POLYTHERAPY AT SICK OF THE EPILEPSY WITH PARTIAL AND GENERALIZED TONIC-CLONIC CONVULSIVE ATTACKS
title_full EXPERIENCE OF APPLICATION OF SAZAR IN POLYTHERAPY AT SICK OF THE EPILEPSY WITH PARTIAL AND GENERALIZED TONIC-CLONIC CONVULSIVE ATTACKS
title_fullStr EXPERIENCE OF APPLICATION OF SAZAR IN POLYTHERAPY AT SICK OF THE EPILEPSY WITH PARTIAL AND GENERALIZED TONIC-CLONIC CONVULSIVE ATTACKS
title_full_unstemmed EXPERIENCE OF APPLICATION OF SAZAR IN POLYTHERAPY AT SICK OF THE EPILEPSY WITH PARTIAL AND GENERALIZED TONIC-CLONIC CONVULSIVE ATTACKS
title_short EXPERIENCE OF APPLICATION OF SAZAR IN POLYTHERAPY AT SICK OF THE EPILEPSY WITH PARTIAL AND GENERALIZED TONIC-CLONIC CONVULSIVE ATTACKS
title_sort experience of application of sazar in polytherapy at sick of the epilepsy with partial and generalized tonic clonic convulsive attacks
topic sazar
epilepsy
symptomatic
cryptogene
idiopathic
hamilton anxiety rating scale (hars)
an index of kerdo
url https://www.epilepsia.su/jour/article/view/271
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AT evsorokova experienceofapplicationofsazarinpolytherapyatsickoftheepilepsywithpartialandgeneralizedtonicclonicconvulsiveattacks
AT aylazarev experienceofapplicationofsazarinpolytherapyatsickoftheepilepsywithpartialandgeneralizedtonicclonicconvulsiveattacks