Evaluation of Antimicrobial Agents, Irrigation Solutions, and Surface Disinfection Techniques for Preventing Bacterial Contamination and Biofilm Formation on Implant Surfaces In Vitro
Background: Peri-implant diseases, driven by bacterial biofilms, threaten long-term implant success. This study evaluated various antimicrobial agents for preventing bacterial contamination and biofilm formation on implant surfaces. Methods: Ultraviolet radiation type C (UV-C) light, povidone-iodine...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_1144_24 |
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| _version_ | 1841543530966679552 |
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| author | PS Priyadharsana Vertika Dubey Prabhleen Kaur Priya Nagar J Chethan BB Priyanka |
| author_facet | PS Priyadharsana Vertika Dubey Prabhleen Kaur Priya Nagar J Chethan BB Priyanka |
| author_sort | PS Priyadharsana |
| collection | DOAJ |
| description | Background:
Peri-implant diseases, driven by bacterial biofilms, threaten long-term implant success. This study evaluated various antimicrobial agents for preventing bacterial contamination and biofilm formation on implant surfaces.
Methods:
Ultraviolet radiation type C (UV-C) light, povidone-iodine (PVP-I), chlorhexidine (CHX), and hydrogen peroxide (H2O2) were tested against bacterial cultures. Log reduction values quantified bacterial population decrease. Biofilm formation was assessed using crystal violet staining and optical density at 570 (OD570) measurements.
Results:
UV-C and PVP-I showed the highest log reductions (3.7067, 3.6200), followed by CHX (2.9467) and H2O2 (2.3800). UV-C and PVP-I most effectively inhibited biofilm formation (OD570: 0.0600, 0.0800), followed by CHX (0.1200) and H2O2 (0.1767).
Conclusion:
UV-C and PVP-I demonstrated superior efficacy in reducing bacterial load and inhibiting biofilm formation, suggesting potential as valuable tools for preventing and managing peri-implant infections. |
| format | Article |
| id | doaj-art-497b21dbe7e4469880ec3e656cf27e50 |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-497b21dbe7e4469880ec3e656cf27e502025-01-13T10:11:22ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3631S363310.4103/jpbs.jpbs_1144_24Evaluation of Antimicrobial Agents, Irrigation Solutions, and Surface Disinfection Techniques for Preventing Bacterial Contamination and Biofilm Formation on Implant Surfaces In VitroPS PriyadharsanaVertika DubeyPrabhleen KaurPriya NagarJ ChethanBB PriyankaBackground: Peri-implant diseases, driven by bacterial biofilms, threaten long-term implant success. This study evaluated various antimicrobial agents for preventing bacterial contamination and biofilm formation on implant surfaces. Methods: Ultraviolet radiation type C (UV-C) light, povidone-iodine (PVP-I), chlorhexidine (CHX), and hydrogen peroxide (H2O2) were tested against bacterial cultures. Log reduction values quantified bacterial population decrease. Biofilm formation was assessed using crystal violet staining and optical density at 570 (OD570) measurements. Results: UV-C and PVP-I showed the highest log reductions (3.7067, 3.6200), followed by CHX (2.9467) and H2O2 (2.3800). UV-C and PVP-I most effectively inhibited biofilm formation (OD570: 0.0600, 0.0800), followed by CHX (0.1200) and H2O2 (0.1767). Conclusion: UV-C and PVP-I demonstrated superior efficacy in reducing bacterial load and inhibiting biofilm formation, suggesting potential as valuable tools for preventing and managing peri-implant infections.https://journals.lww.com/10.4103/jpbs.jpbs_1144_24antimicrobial agentschlorhexidinehydrogen peroxideperi-implant diseasespovidone-iodineultraviolet radiation |
| spellingShingle | PS Priyadharsana Vertika Dubey Prabhleen Kaur Priya Nagar J Chethan BB Priyanka Evaluation of Antimicrobial Agents, Irrigation Solutions, and Surface Disinfection Techniques for Preventing Bacterial Contamination and Biofilm Formation on Implant Surfaces In Vitro Journal of Pharmacy and Bioallied Sciences antimicrobial agents chlorhexidine hydrogen peroxide peri-implant diseases povidone-iodine ultraviolet radiation |
| title | Evaluation of Antimicrobial Agents, Irrigation Solutions, and Surface Disinfection Techniques for Preventing Bacterial Contamination and Biofilm Formation on Implant Surfaces In Vitro |
| title_full | Evaluation of Antimicrobial Agents, Irrigation Solutions, and Surface Disinfection Techniques for Preventing Bacterial Contamination and Biofilm Formation on Implant Surfaces In Vitro |
| title_fullStr | Evaluation of Antimicrobial Agents, Irrigation Solutions, and Surface Disinfection Techniques for Preventing Bacterial Contamination and Biofilm Formation on Implant Surfaces In Vitro |
| title_full_unstemmed | Evaluation of Antimicrobial Agents, Irrigation Solutions, and Surface Disinfection Techniques for Preventing Bacterial Contamination and Biofilm Formation on Implant Surfaces In Vitro |
| title_short | Evaluation of Antimicrobial Agents, Irrigation Solutions, and Surface Disinfection Techniques for Preventing Bacterial Contamination and Biofilm Formation on Implant Surfaces In Vitro |
| title_sort | evaluation of antimicrobial agents irrigation solutions and surface disinfection techniques for preventing bacterial contamination and biofilm formation on implant surfaces in vitro |
| topic | antimicrobial agents chlorhexidine hydrogen peroxide peri-implant diseases povidone-iodine ultraviolet radiation |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_1144_24 |
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