Quality of Life in Osteoarthritis: Relationship with Demographic and Clinical Variables

Objective:To investigate the relationship of quality of life (QoL) with demographic and clinical variables in osteoarthritis (OA).Materials and Methods:QoL of 156 patients (79.5% female) with the knee, hip, foot, and/or hand OA was assessed by the OAQoL scale. Zero-10 numeric rating scale (NRS) for...

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Main Authors: Seçilay Güneş, Beyza Doğanay Erdoğan, Şehim Kutlay, Ayşe Adile Küçükdeveci
Format: Article
Language:English
Published: Galenos Publishing House 2022-04-01
Series:Türk Osteoporoz Dergisi
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Online Access: http://www.turkosteoporozdergisi.org/archives/archive-detail/article-preview/quality-of-life-in-osteoarthritis-relationship-wit/51341
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author Seçilay Güneş
Beyza Doğanay Erdoğan
Şehim Kutlay
Ayşe Adile Küçükdeveci
author_facet Seçilay Güneş
Beyza Doğanay Erdoğan
Şehim Kutlay
Ayşe Adile Küçükdeveci
author_sort Seçilay Güneş
collection DOAJ
description Objective:To investigate the relationship of quality of life (QoL) with demographic and clinical variables in osteoarthritis (OA).Materials and Methods:QoL of 156 patients (79.5% female) with the knee, hip, foot, and/or hand OA was assessed by the OAQoL scale. Zero-10 numeric rating scale (NRS) for pain severity, Health Assessment Questionnaire (HAQ) for general physical disability, Western Ontario and McMaster Universities Index of Osteoarthritis (WOMAC) for knee/hip disability, and the Nottingham Health Profile (NHP) for health status were also completed by patients.Results:Mean age was 56±10 and mean disease duration 7.2±6.4 years. There were moderate-to-strong significant correlations (r=0.50-0.70) between QoL and HAQ, WOMAC-pain, WOMAC-function, WOMAC-stiffness, NHP-physical mobility, and NHP-energy. QoL was not related to the number of joints affected by osteoarthritis. A linear regression model was performed to determine the factors that together explain the variability in QoL. Potential variables which found statistically significant in univariate linear regression analyses were used in a stepwise regression procedure to select the final multivariate model. The final model included pain (NRS), HAQ, NHP-energy, and NHP-social isolation with an adjusted R2 of 0.645.Conclusion:Pain, physical function, fatigue, and social isolation have been found to be the predictors of QoL in this osteoarthritis patient group, explaining 64.5% of the variance.
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series Türk Osteoporoz Dergisi
spelling doaj-art-49772bcd6b78439f97d76ae4a71197a42025-08-20T03:36:48ZengGalenos Publishing HouseTürk Osteoporoz Dergisi2147-26532022-04-01281556010.4274/tod.galenos.2022.7338313049054Quality of Life in Osteoarthritis: Relationship with Demographic and Clinical VariablesSeçilay Güneş0Beyza Doğanay Erdoğan1Şehim Kutlay2Ayşe Adile Küçükdeveci3 Ankara University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Ankara, Turkey Ankara University Faculty of Medicine, Department of Biostatistics, Ankara, Turkey Ankara University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Ankara, Turkey Ankara University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Ankara, Turkey Objective:To investigate the relationship of quality of life (QoL) with demographic and clinical variables in osteoarthritis (OA).Materials and Methods:QoL of 156 patients (79.5% female) with the knee, hip, foot, and/or hand OA was assessed by the OAQoL scale. Zero-10 numeric rating scale (NRS) for pain severity, Health Assessment Questionnaire (HAQ) for general physical disability, Western Ontario and McMaster Universities Index of Osteoarthritis (WOMAC) for knee/hip disability, and the Nottingham Health Profile (NHP) for health status were also completed by patients.Results:Mean age was 56±10 and mean disease duration 7.2±6.4 years. There were moderate-to-strong significant correlations (r=0.50-0.70) between QoL and HAQ, WOMAC-pain, WOMAC-function, WOMAC-stiffness, NHP-physical mobility, and NHP-energy. QoL was not related to the number of joints affected by osteoarthritis. A linear regression model was performed to determine the factors that together explain the variability in QoL. Potential variables which found statistically significant in univariate linear regression analyses were used in a stepwise regression procedure to select the final multivariate model. The final model included pain (NRS), HAQ, NHP-energy, and NHP-social isolation with an adjusted R2 of 0.645.Conclusion:Pain, physical function, fatigue, and social isolation have been found to be the predictors of QoL in this osteoarthritis patient group, explaining 64.5% of the variance. http://www.turkosteoporozdergisi.org/archives/archive-detail/article-preview/quality-of-life-in-osteoarthritis-relationship-wit/51341 osteoarthritisquality of lifepainphysical functionphysical disability
spellingShingle Seçilay Güneş
Beyza Doğanay Erdoğan
Şehim Kutlay
Ayşe Adile Küçükdeveci
Quality of Life in Osteoarthritis: Relationship with Demographic and Clinical Variables
Türk Osteoporoz Dergisi
osteoarthritis
quality of life
pain
physical function
physical disability
title Quality of Life in Osteoarthritis: Relationship with Demographic and Clinical Variables
title_full Quality of Life in Osteoarthritis: Relationship with Demographic and Clinical Variables
title_fullStr Quality of Life in Osteoarthritis: Relationship with Demographic and Clinical Variables
title_full_unstemmed Quality of Life in Osteoarthritis: Relationship with Demographic and Clinical Variables
title_short Quality of Life in Osteoarthritis: Relationship with Demographic and Clinical Variables
title_sort quality of life in osteoarthritis relationship with demographic and clinical variables
topic osteoarthritis
quality of life
pain
physical function
physical disability
url http://www.turkosteoporozdergisi.org/archives/archive-detail/article-preview/quality-of-life-in-osteoarthritis-relationship-wit/51341
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AT ayseadilekucukdeveci qualityoflifeinosteoarthritisrelationshipwithdemographicandclinicalvariables