Marine-Derived Peptides from <i>Phaeodactylum tricornutum</i> as Potential SARS-CoV-2 Mpro Inhibitors: An <i>In Silico</i> Approach

Marine-Derived Peptides from <i>Phaeodactylum tricornutum</i> as Potential SARS-CoV-2 Mpro Inhibitors: An <i>In Silico</i> Approach

The ongoing threat of viral pandemics such as COVID-19 highlights the urgent need for novel antiviral therapeutics targeting conserved viral proteins. In this study, peptides of 10–30 kDa derived from the marine diatom <i>Phaeodactylum tricornutum</i> were identified as potential inhibit...

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Main Authors: David Mauricio Cañedo-Figueroa, Marco Antonio Valdez-Flores, Claudia Desireé Norzagaray-Valenzuela, Loranda Calderón-Zamora, Ángel Radamés Rábago-Monzón, Josué Camberos-Barraza, Alma Marlene Guadrón-Llanos, Alberto Kousuke De la Herrán-Arita, Verónica Judith Picos-Cárdenas, Alejandro Camacho-Zamora, Alejandra Romero-Utrilla, Carlos Daniel Cordero-Rivera, Rosa María del Ángel, Moisés León-Juárez, José Manuel Reyes-Ruiz, Carlos Noe Farfan-Morales, Luis Adrián De Jesús-González, Juan Fidel Osuna-Ramos
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Microorganisms
Subjects:
antiviral peptides
SARS-CoV-2
main protease (Mpro)
<i>Phaeodactylum tricornutum</i>
<i>in silico</i> analysis
Online Access:https://www.mdpi.com/2076-2607/13/6/1271
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