Bispecific antibody targeting TROP2xCD3 suppresses tumor growth of triple negative breast cancer

Background Triple negative breast cancer (TNBC) is a subtype of breast cancers with poor prognosis and targeted drug therapies are limited. To develop novel and efficacious therapies for TNBC, we developed a bispecific antibody F7AK3 that recognizes both trophoblast cell surface antigen 2 (TROP2) an...

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Bibliographic Details
Main Authors: Jing Wang, Lin Li, Huicheng Liu, Lili Bai, Liu Huang, Na Ning, Yijia Li, Xuejiao Dong, Qiuyang Du, Minghui Xia, Yufei Chen, Likun Zhao, Yanhu Li, Qingwu Meng, Yaqi Duan, Jie Ming, Andy Qingan Yuan, Xiang-Ping Yang
Format: Article
Language:English
Published: BMJ Publishing Group 2021-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/10/e003468.full
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