Management of non-Cardiac Organ Failure in cardiogenic shock
Cardiogenic shock (CS) is a syndrome of low cardiac output leading to systemic hypoperfusion. The mainstay of management involves optimizing preload, afterload, and contractility to restore central hemodynamics. However, CS is frequently complicated by non-cardiac organ failure, for which there is l...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | American Heart Journal Plus |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666602225000527 |
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| author | Chirag Mehta Abraham Shin Brian Osorio Daniel DePolo Irene Vargas Emily Hao Ali Khan Sahas Chandragiri Sandipan Shringi Paige O. McLean Diaz Nicholas S. Potter Mark Godding Athena Poppas Rachna Kataria Marwan Saad Omar Hyder Neel R. Sodha J. Dawn Abbott Saraschandra Vallabhajosyula |
| author_facet | Chirag Mehta Abraham Shin Brian Osorio Daniel DePolo Irene Vargas Emily Hao Ali Khan Sahas Chandragiri Sandipan Shringi Paige O. McLean Diaz Nicholas S. Potter Mark Godding Athena Poppas Rachna Kataria Marwan Saad Omar Hyder Neel R. Sodha J. Dawn Abbott Saraschandra Vallabhajosyula |
| author_sort | Chirag Mehta |
| collection | DOAJ |
| description | Cardiogenic shock (CS) is a syndrome of low cardiac output leading to systemic hypoperfusion. The mainstay of management involves optimizing preload, afterload, and contractility to restore central hemodynamics. However, CS is frequently complicated by non-cardiac organ failure, for which there is limited guidance. Herein, we review the pathophysiology, assessment, and management of respiratory, renal, hepatic, and neurological failure in the context of CS. This review is intended to provide an evidence-based framework for the management of extracardiac sequelae for the patients in the cardiac and medical intensive care unit. |
| format | Article |
| id | doaj-art-496aafd0f5c2498796d2d72726fb3fa2 |
| institution | OA Journals |
| issn | 2666-6022 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Heart Journal Plus |
| spelling | doaj-art-496aafd0f5c2498796d2d72726fb3fa22025-08-20T02:30:39ZengElsevierAmerican Heart Journal Plus2666-60222025-07-015510054910.1016/j.ahjo.2025.100549Management of non-Cardiac Organ Failure in cardiogenic shockChirag Mehta0Abraham Shin1Brian Osorio2Daniel DePolo3Irene Vargas4Emily Hao5Ali Khan6Sahas Chandragiri7Sandipan Shringi8Paige O. McLean Diaz9Nicholas S. Potter10Mark Godding11Athena Poppas12Rachna Kataria13Marwan Saad14Omar Hyder15Neel R. Sodha16J. Dawn Abbott17Saraschandra Vallabhajosyula18Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaWarren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDivision of Kidney Disease and Hypertension, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDivision of Gastroenterology, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDivision of Neurocritical Care, Departments of Neurology and Neurosurgery, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDivision of Cardiology, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDivision of Cardiology, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America; Brown University Health Cardiovascular Institute, Providence, Rhode Island, United States of AmericaDivision of Cardiology, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America; Brown University Health Cardiovascular Institute, Providence, Rhode Island, United States of AmericaDivision of Cardiology, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America; Brown University Health Cardiovascular Institute, Providence, Rhode Island, United States of AmericaDivision of Cardiology, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America; Brown University Health Cardiovascular Institute, Providence, Rhode Island, United States of AmericaBrown University Health Cardiovascular Institute, Providence, Rhode Island, United States of America; Division of Cardiothoracic Surgery, Department of Surgery, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of AmericaDivision of Cardiology, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America; Brown University Health Cardiovascular Institute, Providence, Rhode Island, United States of AmericaDivision of Cardiology, Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America; Brown University Health Cardiovascular Institute, Providence, Rhode Island, United States of America; Corresponding author at: Warren Alpert Medical School of Brown University, 2 Dudley Street, Suite 360, Providence, Rhode Island 02905, United States of America.Cardiogenic shock (CS) is a syndrome of low cardiac output leading to systemic hypoperfusion. The mainstay of management involves optimizing preload, afterload, and contractility to restore central hemodynamics. However, CS is frequently complicated by non-cardiac organ failure, for which there is limited guidance. Herein, we review the pathophysiology, assessment, and management of respiratory, renal, hepatic, and neurological failure in the context of CS. This review is intended to provide an evidence-based framework for the management of extracardiac sequelae for the patients in the cardiac and medical intensive care unit.http://www.sciencedirect.com/science/article/pii/S2666602225000527Cardiogenic shockRespiratory failureRenal failureNeurologic failureCardiac intensive care unit |
| spellingShingle | Chirag Mehta Abraham Shin Brian Osorio Daniel DePolo Irene Vargas Emily Hao Ali Khan Sahas Chandragiri Sandipan Shringi Paige O. McLean Diaz Nicholas S. Potter Mark Godding Athena Poppas Rachna Kataria Marwan Saad Omar Hyder Neel R. Sodha J. Dawn Abbott Saraschandra Vallabhajosyula Management of non-Cardiac Organ Failure in cardiogenic shock American Heart Journal Plus Cardiogenic shock Respiratory failure Renal failure Neurologic failure Cardiac intensive care unit |
| title | Management of non-Cardiac Organ Failure in cardiogenic shock |
| title_full | Management of non-Cardiac Organ Failure in cardiogenic shock |
| title_fullStr | Management of non-Cardiac Organ Failure in cardiogenic shock |
| title_full_unstemmed | Management of non-Cardiac Organ Failure in cardiogenic shock |
| title_short | Management of non-Cardiac Organ Failure in cardiogenic shock |
| title_sort | management of non cardiac organ failure in cardiogenic shock |
| topic | Cardiogenic shock Respiratory failure Renal failure Neurologic failure Cardiac intensive care unit |
| url | http://www.sciencedirect.com/science/article/pii/S2666602225000527 |
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