The landscape of chemokine and cytokine is associated with the distinct clinical status of leprosy patients and their respective household contacts

The landscape of chemokine and cytokine is associated with the distinct clinical status of leprosy patients and their respective household contacts

IntroductionLeprosy, a chronic infectious disease, is closely linked to the host immune response. According to the WHO, leprosy patients (L) and household contacts (HHC) are classified into subgroups: paucibacillary (PB) and multibacillary (MB), witch reflect the degree of infection in patients and...

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Main Authors: Lorena Bruna Pereira de Oliveira, Pedro Henrique Ferreira Marçal, Karolina Dias Campos, Daisy Cristina Monteiro dos Santos, Marlucy Rodrigues Lima, Olindo Assis Martins-Filho, Joaquim Pedro Brito-de-Sousa, Thais Abdala-Torres, Roberta Olmo Pinheiro, Euzenir Nunes Sarno, Jessica K. Fairley, Lucia Alves de Oliveira Fraga
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
leprosy
Mycobacterium leprae
cytokines
chemokines
household contacts
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1476450/full
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