Anticariogenic Potential of Tabernaemontana Divaricata

Context: Many parts of Tabernaemontana divaricata (T. divaricata) including its leaf is used for the analgesic and antibacterial purpose by Adivasis of Kerala. Aims: To evaluate the antibacterial potential of T. divaricata against common caries pathogens like S. mutans and L. acidophilus. Settings a...

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Main Authors: Mini K. John, David Z. Cheriyan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-07-01
Series:Indian Journal of Dental Research
Subjects:
Online Access:https://journals.lww.com/10.4103/ijdr.IJDR_444_20
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author Mini K. John
David Z. Cheriyan
author_facet Mini K. John
David Z. Cheriyan
author_sort Mini K. John
collection DOAJ
description Context: Many parts of Tabernaemontana divaricata (T. divaricata) including its leaf is used for the analgesic and antibacterial purpose by Adivasis of Kerala. Aims: To evaluate the antibacterial potential of T. divaricata against common caries pathogens like S. mutans and L. acidophilus. Settings and Design: Research is done in Biogenix Research Lab, Thiruvananthapuram. Methods and Material: Ethyl alcoholic extract of T. divaricata leaves is tested for its antibacterial action against common caries pathogens at various levels. It includes assessing the leaves’ antibacterial activity, acid production of bacteria in the presence of the study sample, Minimum inhibitory concentration (MIC), minimum bacterial concentration (MBC) and colony forming units (CFU) levels in the presence of the leaf extract. Statistical Analysis Used: In descriptive statistics, mean and standard deviation is used. Mann–Whitney U test, Independent Students T-test, Student Paired T-test, and One-way ANOVA followed by Turkeys Post hoc analysis are the tests used in inferential statistics. Results: It is found that T. divaricata has substantial antibacterial action against S. mutans and L. acidophilus. Conclusions: Our indigenous plants have a lot of medicinal properties. T. divaricata is no exception to this, though it is commonly considered as a garden plant. In the current study, it has been proven that its leaves have antibacterial action against oral pathogens. So, the research has to be taken to a further level for its medicinal application.
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institution Kabale University
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publishDate 2023-07-01
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spelling doaj-art-4943ffa1fbf3408b859c8cd8fc944ab52025-02-10T07:14:32ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032023-07-0134324224610.4103/ijdr.IJDR_444_20Anticariogenic Potential of Tabernaemontana DivaricataMini K. JohnDavid Z. CheriyanContext: Many parts of Tabernaemontana divaricata (T. divaricata) including its leaf is used for the analgesic and antibacterial purpose by Adivasis of Kerala. Aims: To evaluate the antibacterial potential of T. divaricata against common caries pathogens like S. mutans and L. acidophilus. Settings and Design: Research is done in Biogenix Research Lab, Thiruvananthapuram. Methods and Material: Ethyl alcoholic extract of T. divaricata leaves is tested for its antibacterial action against common caries pathogens at various levels. It includes assessing the leaves’ antibacterial activity, acid production of bacteria in the presence of the study sample, Minimum inhibitory concentration (MIC), minimum bacterial concentration (MBC) and colony forming units (CFU) levels in the presence of the leaf extract. Statistical Analysis Used: In descriptive statistics, mean and standard deviation is used. Mann–Whitney U test, Independent Students T-test, Student Paired T-test, and One-way ANOVA followed by Turkeys Post hoc analysis are the tests used in inferential statistics. Results: It is found that T. divaricata has substantial antibacterial action against S. mutans and L. acidophilus. Conclusions: Our indigenous plants have a lot of medicinal properties. T. divaricata is no exception to this, though it is commonly considered as a garden plant. In the current study, it has been proven that its leaves have antibacterial action against oral pathogens. So, the research has to be taken to a further level for its medicinal application.https://journals.lww.com/10.4103/ijdr.IJDR_444_20lactobacillus acidophilusstreptococcus mutanstabernaemontana divaricata
spellingShingle Mini K. John
David Z. Cheriyan
Anticariogenic Potential of Tabernaemontana Divaricata
Indian Journal of Dental Research
lactobacillus acidophilus
streptococcus mutans
tabernaemontana divaricata
title Anticariogenic Potential of Tabernaemontana Divaricata
title_full Anticariogenic Potential of Tabernaemontana Divaricata
title_fullStr Anticariogenic Potential of Tabernaemontana Divaricata
title_full_unstemmed Anticariogenic Potential of Tabernaemontana Divaricata
title_short Anticariogenic Potential of Tabernaemontana Divaricata
title_sort anticariogenic potential of tabernaemontana divaricata
topic lactobacillus acidophilus
streptococcus mutans
tabernaemontana divaricata
url https://journals.lww.com/10.4103/ijdr.IJDR_444_20
work_keys_str_mv AT minikjohn anticariogenicpotentialoftabernaemontanadivaricata
AT davidzcheriyan anticariogenicpotentialoftabernaemontanadivaricata