Polyhydroxyalkanoates Production from Fruit Waste Using Bacillus Strain from Wastewater Sludge

Polyhydroxyalkanoates (PHAs) are biodegradable polymers produced through microbial fermentation. However, the high costs associated with traditional feedstocks and fermentation techniques limit their economic feasibility. In this study, PHA-producing strains were screened from sludge samples collect...

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Main Authors: Chung-Mao Ou, Hui-Jun Wang, Chun-Mei Huang, Gia-Luen Guo
Format: Article
Language:English
Published: North Carolina State University 2025-06-01
Series:BioResources
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Online Access:https://ojs.bioresources.com/index.php/BRJ/article/view/24136
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author Chung-Mao Ou
Hui-Jun Wang
Chun-Mei Huang
Gia-Luen Guo
author_facet Chung-Mao Ou
Hui-Jun Wang
Chun-Mei Huang
Gia-Luen Guo
author_sort Chung-Mao Ou
collection DOAJ
description Polyhydroxyalkanoates (PHAs) are biodegradable polymers produced through microbial fermentation. However, the high costs associated with traditional feedstocks and fermentation techniques limit their economic feasibility. In this study, PHA-producing strains were screened from sludge samples collected at a wastewater treatment plant in Hsinchu, Taiwan. Nile red fluorescence staining and polymerase chain reaction (PCR) were used to detect the polyhydroxyalkanoate synthase (phaC) gene fragment, leading to the selection of a high-yield PHA-producing Bacillus strain for further investigation. This strain can utilize various inexpensive substrates and exhibits rapid growth, enabling efficient polyhydroxybutyrate (PHB) production without the need for sterilization or costly pretreatment processes. When fruit waste was used as the substrate, the PHB content reached 17.94%, and the PHA production yield reached 2.12 g/L. These results demonstrate the feasibility of non-sterilized fermentation using low-cost waste materials, significantly reducing the overall production costs of PHAs and providing a promising strategy for economically efficient PHB production.
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institution Kabale University
issn 1930-2126
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publishDate 2025-06-01
publisher North Carolina State University
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series BioResources
spelling doaj-art-4937e62e10ca416b95a6cdd02ac5eb622025-08-20T03:45:02ZengNorth Carolina State UniversityBioResources1930-21262025-06-01203677967872377Polyhydroxyalkanoates Production from Fruit Waste Using Bacillus Strain from Wastewater SludgeChung-Mao Ou0Hui-Jun Wang1Chun-Mei Huang2Gia-Luen Guo3Department of Chemistry, National Atomic Research Institute, No. 1000, Wenhua Road, Jiaan Village, Longtan District, Taoyuan City, 325207, Taiwan (R.O.C)Department of Chemistry, National Atomic Research Institute, No. 1000, Wenhua Road, Jiaan Village, Longtan District, Taoyuan City, 325207, Taiwan (R.O.C)Department of Chemistry, National Atomic Research Institute, No. 1000, Wenhua Road, Jiaan Village, Longtan District, Taoyuan City, 325207, Taiwan (R.O.C)Department of Chemistry, National Atomic Research Institute, No. 1000, Wenhua Road, Jiaan Village, Longtan District, Taoyuan City, 325207, Taiwan (R.O.C)Polyhydroxyalkanoates (PHAs) are biodegradable polymers produced through microbial fermentation. However, the high costs associated with traditional feedstocks and fermentation techniques limit their economic feasibility. In this study, PHA-producing strains were screened from sludge samples collected at a wastewater treatment plant in Hsinchu, Taiwan. Nile red fluorescence staining and polymerase chain reaction (PCR) were used to detect the polyhydroxyalkanoate synthase (phaC) gene fragment, leading to the selection of a high-yield PHA-producing Bacillus strain for further investigation. This strain can utilize various inexpensive substrates and exhibits rapid growth, enabling efficient polyhydroxybutyrate (PHB) production without the need for sterilization or costly pretreatment processes. When fruit waste was used as the substrate, the PHB content reached 17.94%, and the PHA production yield reached 2.12 g/L. These results demonstrate the feasibility of non-sterilized fermentation using low-cost waste materials, significantly reducing the overall production costs of PHAs and providing a promising strategy for economically efficient PHB production.https://ojs.bioresources.com/index.php/BRJ/article/view/24136polyhydroxyalkanoatesfruit wastebacillusnon-sterilized fermentation
spellingShingle Chung-Mao Ou
Hui-Jun Wang
Chun-Mei Huang
Gia-Luen Guo
Polyhydroxyalkanoates Production from Fruit Waste Using Bacillus Strain from Wastewater Sludge
BioResources
polyhydroxyalkanoates
fruit waste
bacillus
non-sterilized fermentation
title Polyhydroxyalkanoates Production from Fruit Waste Using Bacillus Strain from Wastewater Sludge
title_full Polyhydroxyalkanoates Production from Fruit Waste Using Bacillus Strain from Wastewater Sludge
title_fullStr Polyhydroxyalkanoates Production from Fruit Waste Using Bacillus Strain from Wastewater Sludge
title_full_unstemmed Polyhydroxyalkanoates Production from Fruit Waste Using Bacillus Strain from Wastewater Sludge
title_short Polyhydroxyalkanoates Production from Fruit Waste Using Bacillus Strain from Wastewater Sludge
title_sort polyhydroxyalkanoates production from fruit waste using bacillus strain from wastewater sludge
topic polyhydroxyalkanoates
fruit waste
bacillus
non-sterilized fermentation
url https://ojs.bioresources.com/index.php/BRJ/article/view/24136
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AT huijunwang polyhydroxyalkanoatesproductionfromfruitwasteusingbacillusstrainfromwastewatersludge
AT chunmeihuang polyhydroxyalkanoatesproductionfromfruitwasteusingbacillusstrainfromwastewatersludge
AT gialuenguo polyhydroxyalkanoatesproductionfromfruitwasteusingbacillusstrainfromwastewatersludge