Predicting resistance to biological therapy using human leukocyte antigen genes in patients with inflammatory bowel disease

Background: The efficacy of anti-tumor necrosis factor (TNF) therapy in inflammatory bowel disease (IBD) is often compromised by the development of antidrug antibodies. In this setting, the human leukocyte antigen (HLA)-DQA1*05 allele has been significantly associated with the formation of antidrug...

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Bibliographic Details
Main Authors: Ângela Domingues, Ana Carvalho, António Martinho, Caroline Soares, Diana Martins, Paula Sousa, Ricardo Araújo, Eugénia Cancela, Américo Silva, Paula Ministro
Format: Article
Language:English
Published: SAGE Publishing 2025-07-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/17562848251353293
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