Predicting resistance to biological therapy using human leukocyte antigen genes in patients with inflammatory bowel disease
Background: The efficacy of anti-tumor necrosis factor (TNF) therapy in inflammatory bowel disease (IBD) is often compromised by the development of antidrug antibodies. In this setting, the human leukocyte antigen (HLA)-DQA1*05 allele has been significantly associated with the formation of antidrug...
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| Main Authors: | Ângela Domingues, Ana Carvalho, António Martinho, Caroline Soares, Diana Martins, Paula Sousa, Ricardo Araújo, Eugénia Cancela, Américo Silva, Paula Ministro |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2025-07-01
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| Series: | Therapeutic Advances in Gastroenterology |
| Online Access: | https://doi.org/10.1177/17562848251353293 |
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