Isolation and identification of Klebsiella pneumoniae phage ΦK2046: optimizing its antibacterial potential in combination with chlorhexidine

Isolation and identification of Klebsiella pneumoniae phage ΦK2046: optimizing its antibacterial potential in combination with chlorhexidine

Abstract Background Hospital-acquired infections (HAIs) significantly increase morbidity and mortality worldwide, with Klebsiella pneumoniae (K. pneumoniae) being a leading HAI pathogen requiring targeted eradication in healthcare settings. The growing bacterial tolerance to chemical disinfectants,...

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Bibliographic Details
Main Authors: Panjie Hu, Yao Sun, Zeyong Zhong, Sichen Liu, Deyi Zhao, Weijun Chen, Ying Zhang, Zhexiao Ma, Jianming Cao, Tieli Zhou
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Antimicrobial Resistance and Infection Control
Subjects:
Bacteriophages
Chlorhexidine
Composite disinfectant
Klebsiella pneumoniae
Low-susceptibility
Online Access:https://doi.org/10.1186/s13756-025-01548-z
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