The Using of Antimicrobial Peptides in Broiler Feeding

It is well known that alternative food additives are being researched following the prohibition of the addition of antibiotics to poultry feed as growth factors. Recently, antimicrobial peptides (AMPs) have been considered as alternatives to antibiotics. AMPs, produced by bacteria, insects, amphibi...

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Main Authors: Mehmet Akif Özcan, Levent Gülüm, Mustafa Midilli, Muhammet Gören
Format: Article
Language:English
Published: Hasan Eleroğlu 2019-01-01
Series:Turkish Journal of Agriculture: Food Science and Technology
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Online Access:http://www.agrifoodscience.com/index.php/TURJAF/article/view/1275
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author Mehmet Akif Özcan
Levent Gülüm
Mustafa Midilli
Muhammet Gören
author_facet Mehmet Akif Özcan
Levent Gülüm
Mustafa Midilli
Muhammet Gören
author_sort Mehmet Akif Özcan
collection DOAJ
description It is well known that alternative food additives are being researched following the prohibition of the addition of antibiotics to poultry feed as growth factors. Recently, antimicrobial peptides (AMPs) have been considered as alternatives to antibiotics. AMPs, produced by bacteria, insects, amphibians and mammals, as well as by chemical synthesis. In particular, their natural antimicrobial properties and their low tendency to create resistance in micro-organisms suggest that they might be a good alternative to antibiotics. They are not only effective against bacteria, but are also known to be effective against fungi and viruses. In studies on pigs and broiler chickens, they have been shown to be beneficial effects on growth performance, nutrient digestibility, the immune system, intestinal morphology and gut microbiota. Antimicrobial peptides are small biological molecules formed from 12-60 amino acids. AMPs have been reported to kill bacteria, in particular those showing resistance to multiple antibiotics. AMPs block the development of harmful bacteria while encouraging the growth of beneficial bacteria. For instance, it has been reported that sublancin reduces the Clostridium perfringens count while increasing the numbers of Lactobacilli. Furthermore, they have been proved to have a strong effect against Staphylococcus aureus and Pseudomonas aeruginosa. Some of the AMPs used in broiler chicken feeding are sublancin, secropin, magainin, nisin and defensin. These peptides can be used by adding them to feed or to drinking water. This review has attempted to find an answer to the question of whether AMPs added to the feed of broiler chickens can be an alternative to antibiotics by examining previous studies.
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spelling doaj-art-491e587d8348431eabfe760ee5b7bc612025-08-20T02:05:56ZengHasan EleroğluTurkish Journal of Agriculture: Food Science and Technology2148-127X2019-01-01711610.24925/turjaf.v7i1.1-6.12751039The Using of Antimicrobial Peptides in Broiler FeedingMehmet Akif Özcan0Levent Gülüm1Mustafa Midilli2Muhammet GörenDepartment of Plant and Animal Production, Mudurnu Süreyya Astarcı Vocational School, Bolu Abant Izzet Baysal University, 14800 BoluDepartment of Plant and Animal Production, Mudurnu Süreyya Astarcı Vocational School, Bolu Abant Izzet Baysal University, 14800 BoluDepartment of Poultry, Faculty of Agriculture and Natural Sciences, Bolu Abant Izzet Baysal University, 14030It is well known that alternative food additives are being researched following the prohibition of the addition of antibiotics to poultry feed as growth factors. Recently, antimicrobial peptides (AMPs) have been considered as alternatives to antibiotics. AMPs, produced by bacteria, insects, amphibians and mammals, as well as by chemical synthesis. In particular, their natural antimicrobial properties and their low tendency to create resistance in micro-organisms suggest that they might be a good alternative to antibiotics. They are not only effective against bacteria, but are also known to be effective against fungi and viruses. In studies on pigs and broiler chickens, they have been shown to be beneficial effects on growth performance, nutrient digestibility, the immune system, intestinal morphology and gut microbiota. Antimicrobial peptides are small biological molecules formed from 12-60 amino acids. AMPs have been reported to kill bacteria, in particular those showing resistance to multiple antibiotics. AMPs block the development of harmful bacteria while encouraging the growth of beneficial bacteria. For instance, it has been reported that sublancin reduces the Clostridium perfringens count while increasing the numbers of Lactobacilli. Furthermore, they have been proved to have a strong effect against Staphylococcus aureus and Pseudomonas aeruginosa. Some of the AMPs used in broiler chicken feeding are sublancin, secropin, magainin, nisin and defensin. These peptides can be used by adding them to feed or to drinking water. This review has attempted to find an answer to the question of whether AMPs added to the feed of broiler chickens can be an alternative to antibiotics by examining previous studies.http://www.agrifoodscience.com/index.php/TURJAF/article/view/1275antimikrobiyal peptidleretlik piliç beslemebüyütme faktörübakteriyosinsublansin
spellingShingle Mehmet Akif Özcan
Levent Gülüm
Mustafa Midilli
Muhammet Gören
The Using of Antimicrobial Peptides in Broiler Feeding
Turkish Journal of Agriculture: Food Science and Technology
antimikrobiyal peptidler
etlik piliç besleme
büyütme faktörü
bakteriyosin
sublansin
title The Using of Antimicrobial Peptides in Broiler Feeding
title_full The Using of Antimicrobial Peptides in Broiler Feeding
title_fullStr The Using of Antimicrobial Peptides in Broiler Feeding
title_full_unstemmed The Using of Antimicrobial Peptides in Broiler Feeding
title_short The Using of Antimicrobial Peptides in Broiler Feeding
title_sort using of antimicrobial peptides in broiler feeding
topic antimikrobiyal peptidler
etlik piliç besleme
büyütme faktörü
bakteriyosin
sublansin
url http://www.agrifoodscience.com/index.php/TURJAF/article/view/1275
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