CALORIMETRIC OBTAINING OF PHARMACEUTICAL FORM OF PARACETOMOL
The possibility of formation of paracetamol of orthorhombic modification by the method of calorimetry is studied. The studies include technological experiments, optical microscopy, differential scanning calorimetry, X-ray diffraction and IR spectroscopy. It is found that in the result of temperature...
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| Format: | Article |
| Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
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| Online Access: | https://www.pharmjournal.ru/jour/article/view/408 |
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| _version_ | 1849696219215953920 |
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| author | A. P. Belyaev V. P. Rubets V. V. Antipov |
| author_facet | A. P. Belyaev V. P. Rubets V. V. Antipov |
| author_sort | A. P. Belyaev |
| collection | DOAJ |
| description | The possibility of formation of paracetamol of orthorhombic modification by the method of calorimetry is studied. The studies include technological experiments, optical microscopy, differential scanning calorimetry, X-ray diffraction and IR spectroscopy. It is found that in the result of temperature cycling the crystals of paracetamol are modified in the crystals of orthorhombic syngony. Microphotographs, X-ray diffraction patterns, differential scanning spectroscopy curves and absorption spectra are presented. |
| format | Article |
| id | doaj-art-48f971e0570f4394ac0e2bcd56b29d2b |
| institution | DOAJ |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj-art-48f971e0570f4394ac0e2bcd56b29d2b2025-08-20T03:19:32ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01026264408CALORIMETRIC OBTAINING OF PHARMACEUTICAL FORM OF PARACETOMOLA. P. Belyaev0V. P. Rubets1V. V. Antipov2Department of Physical and Colloidal Chemistry. Saint-Petersburg State Chemical Pharmaceutical AcademyDepartment of Analytical Chemistry. Saint Petersburg State Institute of Technology (Technical University)Department of Analytical Chemistry. Saint Petersburg State Institute of Technology (Technical University)The possibility of formation of paracetamol of orthorhombic modification by the method of calorimetry is studied. The studies include technological experiments, optical microscopy, differential scanning calorimetry, X-ray diffraction and IR spectroscopy. It is found that in the result of temperature cycling the crystals of paracetamol are modified in the crystals of orthorhombic syngony. Microphotographs, X-ray diffraction patterns, differential scanning spectroscopy curves and absorption spectra are presented.https://www.pharmjournal.ru/jour/article/view/408paracetamolmodification of crystal structurecalorimetry |
| spellingShingle | A. P. Belyaev V. P. Rubets V. V. Antipov CALORIMETRIC OBTAINING OF PHARMACEUTICAL FORM OF PARACETOMOL Разработка и регистрация лекарственных средств paracetamol modification of crystal structure calorimetry |
| title | CALORIMETRIC OBTAINING OF PHARMACEUTICAL FORM OF PARACETOMOL |
| title_full | CALORIMETRIC OBTAINING OF PHARMACEUTICAL FORM OF PARACETOMOL |
| title_fullStr | CALORIMETRIC OBTAINING OF PHARMACEUTICAL FORM OF PARACETOMOL |
| title_full_unstemmed | CALORIMETRIC OBTAINING OF PHARMACEUTICAL FORM OF PARACETOMOL |
| title_short | CALORIMETRIC OBTAINING OF PHARMACEUTICAL FORM OF PARACETOMOL |
| title_sort | calorimetric obtaining of pharmaceutical form of paracetomol |
| topic | paracetamol modification of crystal structure calorimetry |
| url | https://www.pharmjournal.ru/jour/article/view/408 |
| work_keys_str_mv | AT apbelyaev calorimetricobtainingofpharmaceuticalformofparacetomol AT vprubets calorimetricobtainingofpharmaceuticalformofparacetomol AT vvantipov calorimetricobtainingofpharmaceuticalformofparacetomol |