Can the co-localization of CD8+, PD-1, PD-L1 AND PD-L2 patterns provide guidance in clinical evolution of patients with head and neck cutaneous squamous cell carcinoma?

Objective: Cutaneous Squamous Cell Carcinoma (cSCC) incidence has increased almost 200% in recent years. Blockade of immune checkpoint axes is an effective way to reactivate the host anti-tumor immune response across a variety of cancer types. We aimed to assess the presence of the Programmed cell D...

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Bibliographic Details
Main Authors: Gustavo Nunes Bento, Andre Bandiera de Oliveira Santos, Leandro Luongo Matos, William C. Faquin, Sara I. Pai, Claudio Roberto Cernea
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Brazilian Journal of Otorhinolaryngology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1808869425000758
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